Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 2/20 | 0.45 |
| ▸ | PDE10A | Q9Y233 | 3/20 | 0.43 |
| ▸ | EGFR | P00533 | 6/20 | 0.42 |
| ▸ | BRAF | P15056 | 1/20 | 0.42 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.41 |
| ▸ | FYN | P06241 | 1/20 | 0.40 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.39 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.39 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.39 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.39 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.39 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.39 |
| ▸ | ROS1 | P08922 | 1/20 | 0.38 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.38 |
| ▸ | PDE4A | P27815 | 1/20 | 0.38 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.38 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.38 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26112302 | 0.89 | EGFR (0.47) | ATMPDE10AEGFRBRAFPDE4A | |
| SCHEMBL31469398 | 0.88 | BRAF (0.47) | ATMPDE10AEGFRBRAFPDE4A | |
| SCHEMBL4778871 | 0.86 | PDK1 (0.49) | ATMPDE10AEGFRPDK1FYN | |
| SCHEMBL31352777 | 0.85 | EGFR (0.47) | ATMPDE10AEGFRBRAFPDE4A | |
| SCHEMBL26109496 | 0.85 | EGFR (0.47) | ATMPDE10AEGFRBRAFPDE4A | |
| SCHEMBL26113098 | 0.81 | KIT (0.48) | ATMEGFRBRAF | |
| SCHEMBL26117034 | 0.80 | KIT (0.45) | ATMEGFRBRAF | |
| SCHEMBL26114386 | 0.79 | EGFR (0.41) | PDE10AEGFRBRAFPDE4APDE4B | |
| SCHEMBL26111872 | 0.78 | EGFR (0.38) | ATMPDE10AEGFRBRAFPDE4A | |
| SCHEMBL26111957 | 0.78 | BRAF (0.42) | PDE10AEGFRBRAFPDE4APDE4B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025080784-A1 | EGFR INHIBITORS | BLUEPRINT MEDICINES CORPORATION (US) | 2025-04-17 | — | — | WO | disclosed |