Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LPL | P06858 | 2/20 | 0.47 |
| ▸ | LIPG | Q9Y5X9 | 2/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 7/20 | 0.39 |
| ▸ | CYP2E1 | P05181 | 3/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.39 |
| ▸ | CYP2C8 | P10632 | 3/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.39 |
| ▸ | CYP2A6 | P11509 | 3/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.39 |
| ▸ | CYP2B6 | P20813 | 3/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.39 |
| ▸ | TNF | P01375 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | RPS6KA3 | P51812 | 2/20 | 0.37 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.36 |
| ▸ | KDR | P35968 | 1/20 | 0.36 |
| ▸ | CYP17A1 | P05093 | 5/20 | 0.35 |
| ▸ | CCNC | P24863 | 1/20 | 0.35 |
| ▸ | CDK8 | P49336 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1688458 | 0.88 | LPL (0.47) | LPLLIPGCYP1A2CYP2E1CYP3A4 | |
| SCHEMBL29254217 | 0.80 | HASPIN (0.45) | LPLLIPGTNFPDGFRBKDR | |
| SCHEMBL30800731 | 0.80 | HASPIN (0.45) | LPLLIPGTNFPDGFRBKDR | |
| SCHEMBL12390740 | 0.80 | LIPG (0.56) | LPLLIPGCYP2A6PDGFRBKDR | |
| SCHEMBL31106 | 0.78 | LIPG (0.59) | LPLLIPGCYP2A6PDGFRBKDR | |
| SCHEMBL26626379 | 0.78 | HSP90AA1 (0.35) | LPLLIPGCYP1A2CYP2D6CYP2C19 | |
| SCHEMBL30601336 | 0.78 | HSP90AA1 (0.35) | LPLLIPGCYP1A2CYP2D6CYP2C19 | |
| SCHEMBL18015456 | 0.77 | LPL (0.46) | LPLLIPGMAPTPDGFRBKDR | |
| SCHEMBL25799128 | 0.77 | LIPG (0.62) | LPLLIPGCYP2A6PDGFRBKDR | |
| SCHEMBL12999308 | 0.76 | LIPG (0.56) | LPLLIPGPDGFRBKDRDGAT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025080784-A1 | EGFR INHIBITORS | BLUEPRINT MEDICINES CORPORATION (US) | 2025-04-17 | — | — | WO | disclosed |