SCHEMBL31469447

SCHEMBL31469447

O=[N+]([O-])c1n[nH]c2cnc(Cl)nc12

nearest known ligand 0.40

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
TYRO3 Q06418 1/20 0.40
DYRK1B Q9Y463 1/20 0.40
GALR3 O60755 1/20 0.38
PIN1 Q13526 11/20 0.35
KDM4E B2RXH2 2/20 0.35
MAPT P10636 2/20 0.33
PIM3 Q86V86 1/20 0.33
RXFP1 Q9HBX9 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18130786 0.75 GALR3 (0.39) GALR3MAPT
SCHEMBL29439822 0.75 GALR3 (0.39) GALR3MAPT
SCHEMBL11546073 0.73 GRM4 (0.35) GALR3MAPT
SCHEMBL4037999 0.73 TYRO3 (0.44) TYRO3DYRK1BKDM4E
SCHEMBL18130737 0.71 GABRA1 (0.38) GALR3KDM4EMAPTPIM3
SCHEMBL29229030 0.71 PIN1 (0.41) TYRO3DYRK1BPIN1KDM4EPIM3
SCHEMBL16525458 0.70 TYRO3 (0.42) TYRO3DYRK1BKDM4E
SCHEMBL19970146 0.70 TYRO3 (0.42) TYRO3DYRK1BKDM4E
SCHEMBL30968125 0.70 TYRO3 (0.42) TYRO3DYRK1BKDM4E
SCHEMBL29454447 0.70 TYRO3 (0.42) TYRO3DYRK1BKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119707979-A Synthesis method of drug intermediate 南京江原安迪科正电子研究发展有限公司 2025-03-28 CN disclosed