Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR2 | Q8TDS4 | 6/20 | 0.37 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.37 |
| ▸ | DAO | P14920 | 1/20 | 0.36 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | RECQL | P46063 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | BDKRB1 | P46663 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15824828 | 0.77 | DYRK1A (0.44) | HCAR2GPR35DAOHCAR3RAB9A | |
| SCHEMBL30964220 | 0.75 | MAPT (0.49) | KDM4EALDH1A1POLBMAPTHPGD | |
| SCHEMBL8077189 | 0.74 | HCAR2 (0.44) | HCAR2GPR35DAOHCAR3RAB9A | |
| SCHEMBL1754228 | 0.74 | HCAR2 (0.37) | HCAR2GPR35DAOHCAR3RAB9A | |
| SCHEMBL9957355 | 0.74 | HCAR2 (0.36) | HCAR2GPR35DAORAB9AMEN1 | |
| SCHEMBL7261697 | 0.71 | HCAR2 (0.35) | HCAR2DAOHCAR3RAB9AALDH1A1 | |
| SCHEMBL2589542 | 0.71 | HCAR2 (0.47) | HCAR2DAOHCAR3RAB9AMEN1 | |
| SCHEMBL22558287 | 0.70 | HCAR2 (0.44) | HCAR2DAOKDM4EMEN1POLB | |
| SCHEMBL6109414 | 0.69 | HCAR2 (0.36) | HCAR2DAOHCAR3RAB9A | |
| SCHEMBL6111067 | 0.69 | HCAR2 (0.38) | HCAR2DAOHCAR3RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119707952-B | Thiadiazolidinone derivative with PTPN2/PTPN1 inhibitory activity, and preparation method and application thereof | CHINA PHARMACEUTICAL UNIVERSITY (CN) | 2026-05-26 | — | — | CN | disclosed |
| CN-119707952-A | Thiadiazolidinone derivative with PTPN2/PTPN1 inhibitory activity, and preparation method and application thereof | 中国药科大学 | 2025-03-28 | — | — | CN | disclosed |