Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 1/20 | 0.39 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.36 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.32 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.32 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.32 |
| ▸ | AKT1 | P31749 | 1/20 | 0.31 |
| ▸ | AKT2 | P31751 | 1/20 | 0.31 |
| ▸ | AKT3 | Q9Y243 | 1/20 | 0.31 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.30 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.30 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.30 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.30 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31469731 | 1.00 | DRD2 (0.39) | DRD2TRPA1PDK2SLC6A2SLC6A4 | |
| SCHEMBL31469743 | 0.81 | DRD2 (0.39) | DRD2TRPA1PDK2SLC6A2SLC6A4 | |
| SCHEMBL31469749 | 0.79 | DRD2 (0.41) | DRD2SLC6A2SLC6A4AKT1AKT2 | |
| SCHEMBL31282925 | 0.79 | DRD2 (0.41) | DRD2SLC6A2SLC6A4AKT1AKT2 | |
| SCHEMBL31469759 | 0.79 | DRD2 (0.41) | DRD2SLC6A2SLC6A4AKT1AKT2 | |
| SCHEMBL25389094 | 0.79 | DRD2 (0.41) | DRD2SLC6A2SLC6A4AKT1AKT2 | |
| SCHEMBL25389095 | 0.79 | DRD2 (0.41) | DRD2SLC6A2SLC6A4AKT1AKT2 | |
| SCHEMBL31469756 | 0.76 | DRD2 (0.39) | DRD2TRPA1SLC6A2SLC6A4AKT1 | |
| SCHEMBL31469774 | 0.76 | DRD2 (0.39) | DRD2TRPA1SLC6A2SLC6A4AKT1 | |
| SCHEMBL31469806 | 0.76 | SLC6A2 (0.39) | DRD2SLC6A2SLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025030002-A2 | DGK TARGETING COMPOUNDS AND USES THEREOF | ARVINAS OPERATIONS, INC. (US) | 2025-02-06 | — | — | WO | disclosed |