Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPA1 | O75762 | 1/20 | 0.43 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.34 |
| ▸ | DAO | P14920 | 1/20 | 0.34 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.33 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.33 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | PLAU | P00749 | 1/20 | 0.33 |
| ▸ | MBOAT4 | Q96T53 | 1/20 | 0.33 |
| ▸ | NFE2L2 | Q16236 | 2/20 | 0.33 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.33 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.33 |
| ▸ | MAOB | P27338 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22719068 | 1.00 | TRPA1 (0.43) | TRPA1CYP19A1DAOADRA2AADRA2B | |
| SCHEMBL10245078 | 0.79 | TRPA1 (0.37) | TRPA1CYP19A1DAOADRA2AADRA2B | |
| SCHEMBL3756670 | 0.77 | DAO (0.39) | TRPA1DAOMBOAT4 | |
| SCHEMBL31508083 | 0.77 | CA12 (0.41) | ADRA2AADRA2BADRA2CMAOB | |
| SCHEMBL8015449 | 0.76 | ALDH1A1 (0.31) | — | |
| SCHEMBL23148799 | 0.75 | GBA1 (0.41) | ADRA2AADRA2BADRA2CL3MBTL1PLAU | |
| SCHEMBL9839010 | 0.75 | — | — | |
| SCHEMBL23600947 | 0.75 | CCR1 (0.43) | DAOADRA2AADRA2BADRA2CL3MBTL1 | |
| SCHEMBL31207468 | 0.75 | GBA1 (0.41) | ADRA2AADRA2BADRA2CL3MBTL1PLAU | |
| SCHEMBL1790656 | 0.73 | DAO (0.40) | TRPA1DAOL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025030002-A2 | DGK TARGETING COMPOUNDS AND USES THEREOF | ARVINAS OPERATIONS, INC. (US) | 2025-02-06 | — | — | WO | disclosed |