Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 2/20 | 0.67 |
| ▸ | MEN1 | O00255 | 2/20 | 0.67 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.67 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | MAPT | P10636 | 3/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 2/20 | 0.46 |
| ▸ | USP2 | O75604 | 1/20 | 0.46 |
| ▸ | CA12 | O43570 | 1/20 | 0.45 |
| ▸ | CA1 | P00915 | 1/20 | 0.45 |
| ▸ | CA2 | P00918 | 1/20 | 0.45 |
| ▸ | CA9 | Q16790 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25360904 | 0.85 | MEN1 (0.72) | HPGDMEN1KMT2ATSHRALDH1A1 | |
| SCHEMBL10631063 | 0.85 | HPGD (0.72) | HPGDMEN1KMT2ATSHRALDH1A1 | |
| SCHEMBL10648195 | 0.84 | MAPT (0.55) | HPGDMEN1KMT2ATSHRALDH1A1 | |
| SCHEMBL11682047 | 0.84 | MAPT (0.67) | HPGDMEN1KMT2AALDH1A1MAPT | |
| SCHEMBL1185546 | 0.83 | MEN1 (0.53) | HPGDMEN1KMT2ATSHRALDH1A1 | |
| SCHEMBL10631076 | 0.82 | KMT2A (0.69) | HPGDMEN1KMT2AALDH1A1MAPT | |
| SCHEMBL9573763 | 0.82 | LMNA (0.52) | HPGDMEN1KMT2ATSHRALDH1A1 | |
| SCHEMBL8086920 | 0.81 | KDM4E (0.59) | HPGDMEN1KMT2ATSHRALDH1A1 | |
| SCHEMBL30623198 | 0.78 | PKM (0.67) | HPGDMEN1KMT2AALDH1A1MAPT | |
| SCHEMBL9703402 | 0.78 | PKM (0.67) | HPGDMEN1KMT2AALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025030002-A2 | DGK TARGETING COMPOUNDS AND USES THEREOF | ARVINAS OPERATIONS, INC. (US) | 2025-02-06 | — | — | WO | disclosed |