SCHEMBL31470105

SCHEMBL31470105

CCNCc1nc2c(OC)c(Cl)cc(Cl)c2c(=O)n1C

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TLR7 Q9NYK1 3/20 0.38
ABCB1 P08183 1/20 0.33
HTR1A P08908 1/20 0.32
HTR1D P28221 1/20 0.32
HTR1B P28222 1/20 0.32
HTR2A P28223 1/20 0.32
HTR2C P28335 1/20 0.32
HTR7 P34969 1/20 0.32
HTR2B P41595 1/20 0.32
HTR5A P47898 1/20 0.32
HTR6 P50406 1/20 0.32
KDM4E B2RXH2 1/20 0.32
GAA P10253 1/20 0.32
ALDH1A1 P00352 1/20 0.32
HPGD P15428 1/20 0.32
HDAC6 Q9UBN7 2/20 0.32
ISG15 P05161 1/20 0.32
USP5 P45974 1/20 0.32
USP16 Q9Y5T5 1/20 0.32
USP3 Q9Y6I4 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL613041 0.84 CDK1 (0.41) KDM4EGAAALDH1A1HPGDTYK2
SCHEMBL31470158 0.84 CDK1 (0.41) KDM4EGAAALDH1A1HPGDTYK2
Pbt-434 SCHEMBL7905166 0.83 TLR7 (0.39) TLR7GAAMEN1KMT2A
Pbt-434 SCHEMBL31470112 0.82 TLR7 (0.39) TLR7GAAMEN1KMT2A
SCHEMBL611902 0.81 AADAT (0.33) GAAALDH1A1HPGDTYK2
Pbt-434 SCHEMBL31470149 0.79 TLR7 (0.37) TLR7
SCHEMBL612542 0.77 GRM2 (0.34) ALDH1A1HDAC6ISG15USP5USP16
SCHEMBL611801 0.75 GRM2 (0.36) ALDH1A1DRD1DRD5DRD2DRD4
SCHEMBL8280002 0.75 KDM4E (0.50) HTR1AHTR1DHTR1BHTR2AHTR2C
SCHEMBL7902753 0.74 CDK1 (0.32) TLR7ALDH1A1GRM2MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025059726-A1 NOVEL THERAPY Alterity Therapeutics Limited (AU) 2025-03-27 WO disclosed