SCHEMBL31470179

SCHEMBL31470179

CNC(=O)c1c(Cl)cc(Cl)c(OC)c1[N+](=O)[O-]

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 1/20 0.49
ALDH1A1 P00352 3/20 0.48
HPGD P15428 1/20 0.48
GRIN2D O15399 1/20 0.46
GRIN3B O60391 1/20 0.46
GRIN1 Q05586 1/20 0.46
GRIN2A Q12879 1/20 0.46
GRIN2B Q13224 1/20 0.46
GRIN2C Q14957 1/20 0.46
GRIN3A Q8TCU5 1/20 0.46
KDM4E B2RXH2 2/20 0.41
GAA P10253 2/20 0.41
PKM P14618 1/20 0.40
MEN1 O00255 3/20 0.40
KMT2A Q03164 3/20 0.40
TAS1R3 Q7RTX0 2/20 0.39
TAS1R1 Q7RTX1 2/20 0.39
TAS1R2 Q8TE23 2/20 0.39
TSHR P16473 2/20 0.39
MAPT P10636 3/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL608700 0.85 SMN1; SMN2 (0.64) SMN1; SMN2ALDH1A1HPGDGRIN2DGRIN3B
SCHEMBL611961 0.84 PKM (0.50) SMN1; SMN2ALDH1A1HPGDGRIN2DGRIN3B
SCHEMBL613006 0.83 SMN1; SMN2 (0.47) SMN1; SMN2ALDH1A1HPGDGRIN2DGRIN3B
SCHEMBL8875039 0.81 SMN1; SMN2 (0.61) SMN1; SMN2ALDH1A1HPGDKDM4EPKM
SCHEMBL9573627 0.76 PKM (0.52) SMN1; SMN2ALDH1A1HPGDKDM4EPKM
SCHEMBL612590 0.76 ALDH1A1 (0.53) ALDH1A1HPGDKDM4EGAAMEN1
SCHEMBL9461274 0.73 GRIN2D (0.50) SMN1; SMN2ALDH1A1HPGDGRIN2DGRIN3B
SCHEMBL10745695 0.72 PKM (0.58) SMN1; SMN2ALDH1A1HPGDGRIN2DGRIN3B
SCHEMBL10745995 0.72 PKM (0.51) SMN1; SMN2ALDH1A1HPGDGRIN2DGRIN3B
SCHEMBL9461983 0.71 GRIN2D (0.46) SMN1; SMN2ALDH1A1HPGDGRIN2DGRIN3B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025059726-A1 NOVEL THERAPY Alterity Therapeutics Limited (AU) 2025-03-27 WO disclosed