SCHEMBL31470348

SCHEMBL31470348

CCOC(=O)C1=NOC2(CCCN(C(=O)OC(C)(C)C)CC2)C1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GPR119 Q8TDV5 3/20 0.48
SMN1; SMN2 Q16637 3/20 0.39
ALDH1A1 P00352 2/20 0.39
LMNA P02545 2/20 0.39
NPSR1 Q6W5P4 2/20 0.39
KMT2A Q03164 2/20 0.39
MEN1 O00255 1/20 0.39
GAA P10253 1/20 0.39
ADORA1 P30542 1/20 0.38
TP53 P04637 2/20 0.37
HSD17B10 Q99714 2/20 0.37
MAPT P10636 2/20 0.37
POLB P06746 1/20 0.37
ALOX15 P16050 1/20 0.37
HDAC3 O15379 1/20 0.37
HDAC4 P56524 1/20 0.37
HDAC1 Q13547 1/20 0.37
HDAC7 Q8WUI4 1/20 0.37
HDAC2 Q92769 1/20 0.37
HDAC10 Q969S8 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2401311 0.96 GPR119 (0.52) GPR119SMN1; SMN2ALDH1A1LMNANPSR1
SCHEMBL31470380 0.86 GPR119 (0.53) GPR119SMN1; SMN2KMT2AMEN1TP53
SCHEMBL26289064 0.83 GPR119 (0.47) GPR119SMN1; SMN2KMT2AMEN1USP2
SCHEMBL13811458 0.83 GPR119 (0.57) GPR119SMN1; SMN2ALDH1A1TP53HSD17B10
SCHEMBL31470342 0.82 GPR119 (0.50) GPR119SMN1; SMN2ALDH1A1KMT2AMEN1
SCHEMBL1639199 0.81 GPR119 (0.57) GPR119SMN1; SMN2TP53HSD17B10MAPT
SCHEMBL2310754 0.80 HSD17B10 (0.45) ALDH1A1LMNANPSR1KMT2AMEN1
SCHEMBL12901476 0.79 GPR119 (0.46) GPR119SMN1; SMN2KMT2AMEN1USP2
SCHEMBL12901443 0.79 GPR119 (0.46) GPR119SMN1; SMN2KMT2AMEN1USP2
SCHEMBL12901475 0.79 GPR119 (0.46) GPR119SMN1; SMN2KMT2AMEN1USP2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025077770-A1 FUSED RING COMPOUND AND USE THEREOF IN KRAS INHIBITOR 成都海博为药业有限公司 2025-04-17 WO disclosed