SCHEMBL31470947

SCHEMBL31470947

Fc1cccc(C2CN=C(c3ccccc3)O2)c1

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.43
HPGD P15428 2/20 0.43
MAOB P27338 4/20 0.43
MAOA P21397 1/20 0.43
SMN1; SMN2 Q16637 2/20 0.43
ATM Q13315 2/20 0.43
NPC1 O15118 1/20 0.42
NFKB1 P19838 1/20 0.42
RAB9A P51151 1/20 0.42
NFKB2 Q00653 1/20 0.42
RELA Q04206 1/20 0.42
CYP1A2 P05177 1/20 0.41
CYP3A4 P08684 1/20 0.41
CYP2D6 P10635 1/20 0.41
CYP2C9 P11712 1/20 0.41
CRHBP P24387 1/20 0.41
CYP2C19 P33261 1/20 0.41
CRHR2 Q13324 1/20 0.41
TAAR1 Q96RJ0 1/20 0.38
SCD5 Q86SK9 2/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1548278 0.86 ALDH1A1 (0.54) ALDH1A1HPGDMAOBSMN1; SMN2ATM
SCHEMBL31470938 0.84 MAOB (0.45) ALDH1A1HPGDMAOBMAOASMN1; SMN2
SCHEMBL27907032 0.84 ALDH1A1 (0.51) ALDH1A1HPGDMAOBSMN1; SMN2ATM
SCHEMBL31470934 0.82 MAOB (0.44) ALDH1A1HPGDMAOBSMN1; SMN2ATM
SCHEMBL31470935 0.82 MAOB (0.44) ALDH1A1HPGDMAOBSMN1; SMN2ATM
SCHEMBL34460861 0.77 TSHR (0.50) ALDH1A1HPGDMAOBSMN1; SMN2ATM
SCHEMBL31158568 0.77 TSHR (0.50) ALDH1A1HPGDMAOBSMN1; SMN2ATM
SCHEMBL13446536 0.76 SMN1; SMN2 (0.47) ALDH1A1HPGDSMN1; SMN2ATMNPC1
SCHEMBL13885660 0.75 ALDH1A1 (0.51) ALDH1A1HPGDMAOBMAOASMN1; SMN2
SCHEMBL8610030 0.74 ATM (0.44) ALDH1A1HPGDMAOBMAOASMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119571341-A Synthetic method of oxazoline compound 柳州职业技术大学 2025-03-07 CN disclosed