Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | MAOB | P27338 | 7/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.32 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.32 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.32 |
| ▸ | NCOR2 | Q9Y618 | 2/20 | 0.32 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.32 |
| ▸ | IMPDH2 | P12268 | 1/20 | 0.32 |
| ▸ | PLK1 | P53350 | 1/20 | 0.32 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.32 |
| ▸ | AR | P10275 | 2/20 | 0.31 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27907032 | 0.79 | ALDH1A1 (0.51) | ATMSMN1; SMN2ALDH1A1HPGDMAOB | |
| SCHEMBL1548278 | 0.77 | ALDH1A1 (0.54) | ATMSMN1; SMN2ALDH1A1HPGDMAOB | |
| SCHEMBL8610059 | 0.76 | ALOX5AP (0.38) | ATMSMN1; SMN2ALDH1A1HPGDIMPDH2 | |
| SCHEMBL8539618 | 0.75 | ATM (0.52) | ATMSMN1; SMN2ALDH1A1HPGDMAOB | |
| SCHEMBL8539615 | 0.75 | ATM (0.52) | ATMSMN1; SMN2ALDH1A1HPGDMAOB | |
| SCHEMBL31158568 | 0.75 | TSHR (0.50) | ATMSMN1; SMN2ALDH1A1HPGDMAOB | |
| SCHEMBL34460861 | 0.75 | TSHR (0.50) | ATMSMN1; SMN2ALDH1A1HPGDMAOB | |
| SCHEMBL31470947 | 0.74 | ALDH1A1 (0.43) | ATMSMN1; SMN2ALDH1A1HPGDMAOB | |
| SCHEMBL13885660 | 0.73 | ALDH1A1 (0.51) | ATMSMN1; SMN2ALDH1A1HPGDMAOB | |
| SCHEMBL31470938 | 0.73 | MAOB (0.45) | ATMSMN1; SMN2ALDH1A1HPGDMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5814648-A | N-hydroxyureas as antiinflammatory agents | PFIZER INC. (US) | 1998-09-29 | — | — | US | disclosed |