Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 1/20 | 0.63 |
| ▸ | F13A1 | P00488 | 1/20 | 0.55 |
| ▸ | TGM2 | P21980 | 1/20 | 0.55 |
| ▸ | TGM1 | P22735 | 1/20 | 0.55 |
| ▸ | PARP1 | P09874 | 1/20 | 0.41 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 3/20 | 0.41 |
| ▸ | GCKR | Q14397 | 2/20 | 0.40 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.39 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.38 |
| ▸ | ELOVL6 | Q9H5J4 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | SPR | P35270 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31471875 | 0.91 | HSD11B1 (0.52) | HSD11B1F13A1TGM2TGM1GPR119 | |
| SCHEMBL31472006 | 0.81 | HSD11B1 (0.79) | HSD11B1F13A1TGM2TGM1PARP1 | |
| SCHEMBL15932400 | 0.79 | HSD11B1 (0.64) | HSD11B1F13A1TGM2TGM1PARP1 | |
| SCHEMBL31471811 | 0.79 | HSD11B1 (0.64) | HSD11B1F13A1TGM2TGM1PARP1 | |
| SCHEMBL17075769 | 0.79 | HSD11B1 (0.64) | HSD11B1F13A1TGM2TGM1PARP1 | |
| SCHEMBL17075765 | 0.79 | HSD11B1 (0.64) | HSD11B1F13A1TGM2TGM1PARP1 | |
| SCHEMBL30121356 | 0.78 | HSD11B1 (0.81) | HSD11B1F13A1TGM2TGM1PARP1 | |
| SCHEMBL31471842 | 0.78 | HSD11B1 (0.76) | HSD11B1F13A1TGM2TGM1PARP1 | |
| SCHEMBL5320715 | 0.78 | GCKR (0.52) | GPR119PKMGCKRPOLBMAPT | |
| SCHEMBL12786806 | 0.77 | HSD11B1 (1.00) | HSD11B1F13A1TGM2TGM1GPR119 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025100889-A1 | QUINAZOLINE DERIVATIVE, SALT THEREOF, AND PHARMACEUTICAL COMPOSITION COMPRISING SAME AS ACTIVE INGREDIENT | 한국화학연구원 | 2025-05-15 | — | — | WO | disclosed |