Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2A6 | P11509 | 3/20 | 0.35 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.31 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.31 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.31 |
| ▸ | CHRNB1 | P11230 | 1/20 | 0.31 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.31 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.31 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.31 |
| ▸ | CHRNB3 | Q05901 | 1/20 | 0.31 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.30 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL314720 | 1.00 | CYP2A6 (0.35) | CYP2A6CYP11B2PIK3CGS1PR1CHRNB1 | |
| SCHEMBL1973789 | 0.92 | CHRNB1 (0.34) | CHRNB1CHRNB2CHRNB4CHRNA3CHRNB3 | |
| SCHEMBL1973787 | 0.92 | CHRNB1 (0.34) | CHRNB1CHRNB2CHRNB4CHRNA3CHRNB3 | |
| SCHEMBL2142250 | 0.90 | CHRNB1 (0.41) | CYP11B2PIK3CGCHRNB1CHRNB2CHRNB4 | |
| SCHEMBL2142244 | 0.90 | CHRNB1 (0.41) | CYP11B2PIK3CGCHRNB1CHRNB2CHRNB4 | |
| SCHEMBL2417047 | 0.89 | S1PR1 (0.39) | CYP2A6CYP11B2PIK3CGS1PR1CHRNB1 | |
| SCHEMBL2417043 | 0.89 | S1PR1 (0.39) | CYP2A6CYP11B2PIK3CGS1PR1CHRNB1 | |
| SCHEMBL315032 | 0.88 | CYP1A1 (0.41) | CYP11B2PIK3CGCHRNB2CHRNB4CHRNA3 | |
| SCHEMBL315031 | 0.88 | CYP1A1 (0.41) | CYP11B2PIK3CGCHRNB2CHRNB4CHRNA3 | |
| SCHEMBL314973 | 0.87 | CHRNB1 (0.36) | CHRNB1CHRNB2CHRNB4CHRNA3CHRNB3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8093394-B2 | Derivatives of 5-thioxylopyranose and use of same for treatment | LABORATOIRES FOURNIER S.A. (FR) | 2012-01-10 | — | — | US | disclosed |
| EP-2066683-B1 | DERIVATIVES OF 5-THIOXYLOPYRANOSE AND USE OF SAME FOR TREATMENT | FOURNIER LAB SA (FR) | 2010-11-03 | — | — | EP | disclosed |
| US-20090182013-A1 | Derivatives of 5-Thioxylopyranose and Use of Same for Treatment | LABORATOIRES FOURNIER S.A. (FR) | 2009-07-16 | — | — | US | disclosed |
| EP-2066683-A1 | DERIVATIVES OF 5-THIOXYLOPYRANOSE AND USE OF SAME FOR TREATMENT | LABORATOIRES FOURNIER SA (FR) | 2009-06-10 | — | — | EP | disclosed |
| WO-2008037922-A1 | DERIVATIVES OF 5-THIOXYLOPYRANOSE AND USE OF SAME FOR TREATMENT | LABORATOIRES FOURNIER S.A. (FR) | 2008-04-03 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090182013-A1 | Derivatives of 5-Thioxylopyranose and Use of Same for Treatment | TPMT, PNPO, PPOX | CYP2A6 158/4885CYP11B2 261/4885PIK3CG 1601/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.