SCHEMBL3147274

SCHEMBL3147274

NC(=O)CCCCNS(=O)(=O)c1ccc2ccccc2c1

nearest known ligand 0.73

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.73
NPY1R P25929 1/20 0.61
NPY5R Q15761 1/20 0.61
POLB P06746 1/20 0.54
TBXA2R P21731 1/20 0.54
LMNA P02545 1/20 0.53
GAA P10253 1/20 0.53
SMN1; SMN2 Q16637 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7371174 0.92 ALDH1A1 (0.68) ALDH1A1NPY1RNPY5RPOLBLMNA
SCHEMBL7973186 0.88 ALDH1A1 (0.90) ALDH1A1NPY1RNPY5RTBXA2R
SCHEMBL11626883 0.87 ALDH1A1 (0.67) ALDH1A1NPY1RNPY5RTBXA2RLMNA
SCHEMBL6792727 0.84 ALDH1A1 (1.00) ALDH1A1NPY1RNPY5RTBXA2RLMNA
SCHEMBL1928807 0.84 CYP1A2 (0.67) ALDH1A1NPY1RNPY5RPOLBLMNA
SCHEMBL9927436 0.83 ALDH1A1 (0.68) ALDH1A1NPY1RNPY5RPOLB
Hydrochloric Acid SCHEMBL1846589 0.83 CYP1A2 (0.66) ALDH1A1NPY1RNPY5RPOLB
SCHEMBL6791530 0.82 ALDH1A1 (0.68) ALDH1A1NPY1RNPY5RPOLBLMNA
SCHEMBL6848743 0.82 KAT6A (0.63) ALDH1A1POLB
SCHEMBL22467259 0.82 ALDH1A1 (0.77) ALDH1A1TBXA2RLMNASMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20100004339-A1 Somatostatin Receptor 1 and/or 4 Selective Agonists and Antagonists OY JUVANTIA PHARMA LTD. (FI) 2010-01-07 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100004339-A1 Somatostatin Receptor 1 and/or 4 Selective Agonists and Antagonists SSTR4, SSTR1, SSTR3 ALDH1A1 4124/4885NPY1R 7/4885NPY5R 21/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.