Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.90 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.72 |
| ▸ | NPY1R | P25929 | 1/20 | 0.63 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.63 |
| ▸ | FABP4 | P15090 | 2/20 | 0.59 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.58 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.57 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6792727 | 0.94 | ALDH1A1 (1.00) | ALDH1A1TBXA2RNPY1RNPY5RFABP4 | |
| SCHEMBL6792532 | 0.89 | ALDH1A1 (0.84) | ALDH1A1TBXA2RNPY1RNPY5R | |
| SCHEMBL3147274 | 0.88 | ALDH1A1 (0.73) | ALDH1A1TBXA2RNPY1RNPY5R | |
| SCHEMBL11626883 | 0.86 | ALDH1A1 (0.67) | ALDH1A1TBXA2RNPY1RNPY5R | |
| SCHEMBL7960250 | 0.84 | ALDH1A1 (0.65) | ALDH1A1TBXA2RNPY1RNPY5R | |
| SCHEMBL9567621 | 0.84 | ALDH1A1 (1.00) | ALDH1A1TBXA2RFABP4 | |
| SCHEMBL9869808 | 0.84 | ALDH1A1 (1.00) | ALDH1A1TBXA2RFABP4 | |
| SCHEMBL9567728 | 0.84 | ALDH1A1 (1.00) | ALDH1A1TBXA2RFABP4 | |
| SCHEMBL9869749 | 0.84 | ALDH1A1 (1.00) | ALDH1A1TBXA2RFABP4 | |
| SCHEMBL599970 | 0.84 | ALDH1A1 (1.00) | ALDH1A1TBXA2RFABP4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6271247-B1 | BINDING TO NEUROPEPTIDE RECEPTORS | ADIR ET COMPAGNIE (FR) | 2001-08-07 | — | — | US | disclosed |
| US-6172108-B1 | NEUROPEPTIDE Y RECEPTOR LIGANDS; TREATING PSYCHOLOGICAL, EATING, SLEEP, AND SEXUAL DISORDERS; HYPOTENSIVE, ANXIOLYTIC, ANTIDEPRESSANT, AND ANTIDIABETIC AGENTS | ADIR ET COMPAGNIE (FR) | 2001-01-09 | — | — | US | disclosed |