SCHEMBL31472809

SCHEMBL31472809

O=c1[nH]cnc2c(-c3cccnc3)nc(-c3ccc(N4CCOCC4)cc3)cc12

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PIK3CA P42336 2/20 0.48
PIK3CB P42338 2/20 0.48
PIK3CD O00329 1/20 0.48
SYK P43405 3/20 0.47
PIM1 P11309 1/20 0.47
CLK1 P49759 1/20 0.43
DYRK1A Q13627 1/20 0.43
PDGFRB P09619 1/20 0.43
XDH P47989 1/20 0.43
PIK3CG P48736 1/20 0.43
AURKA O14965 4/20 0.42
LRRK2 Q5S007 1/20 0.42
KDM4E B2RXH2 1/20 0.42
ALDH1A1 P00352 1/20 0.42
MAPT P10636 1/20 0.42
HPGD P15428 1/20 0.42
MAPK1 P28482 1/20 0.42
TDP1 Q9NUW8 1/20 0.42
L3MBTL1 Q9Y468 1/20 0.42
ATR Q13535 2/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23950570 0.82 PSD (0.44) PIM1DYRK1APDGFRBAURKALRRK2
SCHEMBL25463634 0.82 PIM1 (0.44) PIM1PDGFRBKDM4E
SCHEMBL30101871 0.81 PIK3CB (0.41) PIK3CAPIK3CBPIK3CDSYKPIM1
SCHEMBL26275700 0.80 PIM1 (0.43) PIM1PDGFRBKDM4E
SCHEMBL23950529 0.79 PIM1 (0.45) PIM1MAPTL3MBTL1
SCHEMBL30101918 0.79 PIM1 (0.45) PIM1MAPTL3MBTL1
SCHEMBL23950547 0.78 SYK (0.43) PIK3CAPIK3CBSYKPIM1CLK1
SCHEMBL30101980 0.78 PIK3CB (0.40) PIK3CAPIK3CBPIK3CDSYKPIM1
SCHEMBL31472806 0.78 XDH (0.41) PIK3CAPIK3CBPIK3CDSYKPIM1
SCHEMBL30101911 0.77 JAK2 (0.40) PIK3CAPIK3CBSYKPIM1CLK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115443276-B Pyridopyrimidinone derivatives and their use as arene receptor modulators 东亚ST株式会社 2025-04-18 CN disclosed