Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CB | P42338 | 3/20 | 0.40 |
| ▸ | PIK3CD | O00329 | 2/20 | 0.40 |
| ▸ | SYK | P43405 | 3/20 | 0.39 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.39 |
| ▸ | PIK3CG | P48736 | 2/20 | 0.39 |
| ▸ | PIM1 | P11309 | 1/20 | 0.39 |
| ▸ | XDH | P47989 | 1/20 | 0.39 |
| ▸ | ATR | Q13535 | 2/20 | 0.39 |
| ▸ | PRKDC | P78527 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.38 |
| ▸ | ATRIP | Q8WXE1 | 1/20 | 0.38 |
| ▸ | CLK1 | P49759 | 1/20 | 0.38 |
| ▸ | PDE9A | O76083 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30102003 | 0.91 | TNKS (0.39) | SYKPIM1DYRK1ACLK1CLK2 | |
| SCHEMBL30101871 | 0.87 | PIK3CB (0.41) | PIK3CBPIK3CDSYKPIK3CAPIK3CG | |
| SCHEMBL30101960 | 0.83 | PIM1 (0.37) | PIM1ALDH1A1MAPTHPGDL3MBTL1 | |
| SCHEMBL31472806 | 0.82 | XDH (0.41) | PIK3CBPIK3CDSYKPIK3CAPIK3CG | |
| SCHEMBL23925427 | 0.79 | SYK (0.44) | PIK3CBSYKPIK3CAPIK3CGPIM1 | |
| SCHEMBL31472809 | 0.78 | PIK3CA (0.48) | PIK3CBPIK3CDSYKPIK3CAPIK3CG | |
| SCHEMBL30101911 | 0.77 | JAK2 (0.40) | PIK3CBSYKPIK3CAPIK3CGPIM1 | |
| SCHEMBL23950547 | 0.76 | SYK (0.43) | PIK3CBSYKPIK3CAPIK3CGPIM1 | |
| SCHEMBL23950297 | 0.75 | ATR (0.44) | PIK3CBSYKPIK3CAPIK3CGPIM1 | |
| SCHEMBL23925581 | 0.71 | SYK (0.42) | SYKPIM1DYRK1ACLK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115443276-A | Pyridopyrimidinone derivatives and their use as modulators of aromatic hydrocarbon receptors | 东亚ST株式会社 | 2022-12-06 | — | — | CN | claimed |
| CN-115443276-A | Pyridopyrimidinone derivatives and their use as modulators of aromatic hydrocarbon receptors | 东亚ST株式会社 | 2022-12-06 | — | — | CN | disclosed |