Known targets — ChEMBL curated mechanism
ACHECHKACHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNB1CHRNDCHRNECHRNGHRH2OPRM1
The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE known ✓ | P22303 | 1/20 | 0.42 |
| ▸ | CHRM2 known ✓ | P08172 | 1/20 | 0.39 |
| ▸ | CHRM1 known ✓ | P11229 | 1/20 | 0.39 |
| ▸ | CHRM3 known ✓ | P20309 | 1/20 | 0.39 |
| ▸ | DNM1 | Q05193 | 2/20 | 0.55 |
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.51 |
| ▸ | TP53 | P04637 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 3/20 | 0.50 |
| ▸ | BCHE | P06276 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.41 |
| ▸ | MLNR | O43193 | 1/20 | 0.39 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.39 |
| ▸ | ESR1 | P03372 | 1/20 | 0.39 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL9470925 | 0.97 | MEN1 (0.55) | DNM1MEN1KMT2AMAPK1SMN1; SMN2 | |
| Bromide SCHEMBL31472969 | 0.88 | DNM1 (0.56) | DNM1MEN1KMT2AMAPK1SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL9469769 | 0.85 | MEN1 (0.56) | DNM1MEN1KMT2AMAPK1SMN1; SMN2 | |
| Bromide SCHEMBL28602625 | 0.84 | DNM1 (0.74) | DNM1MEN1KMT2AMAPK1SMN1; SMN2 | |
| Bromide SCHEMBL11404008 | 0.84 | DNM1 (0.74) | DNM1MEN1KMT2AMAPK1SMN1; SMN2 | |
| Bromide SCHEMBL28351453 | 0.84 | DNM1 (0.74) | DNM1MEN1KMT2AMAPK1SMN1; SMN2 | |
| Bromide SCHEMBL11276216 | 0.84 | DNM1 (0.74) | DNM1MEN1KMT2AMAPK1SMN1; SMN2 | |
| Bromide SCHEMBL718747 | 0.84 | DNM1 (0.74) | DNM1MEN1KMT2AMAPK1SMN1; SMN2 | |
| Bromide SCHEMBL11306487 | 0.84 | DNM1 (0.74) | DNM1MEN1KMT2AMAPK1SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL9469590 | 0.83 | MEN1 (0.50) | DNM1MEN1KMT2AMAPK1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114392200-B | Preparation method of hair dye and hair dye | 柯煌阳 | 2025-02-07 | — | — | CN | disclosed |