SCHEMBL3147309

SCHEMBL3147309

CC1(C)CC2(CC(C)(C)NC(=O)N2)NC(=O)N1

nearest known ligand 0.36

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
CTSK P43235 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10417041 0.75 CTSK (0.34) CTSKSMN1; SMN2
SCHEMBL223245 0.67
SCHEMBL9729943 0.65 TSHR (0.30)
SCHEMBL16253386 0.65 TDP2 (0.31)
SCHEMBL14136016 0.65 SMN1; SMN2 (0.31) SMN1; SMN2
SCHEMBL9717712 0.64 POLB (0.32)
SCHEMBL1513938 0.64 POLB (0.32)
SCHEMBL13527600 0.64 POLB (0.32)
SCHEMBL15238113 0.64
SCHEMBL7831976 0.63 SMN1; SMN2 (0.44) CTSKSMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2151846-B1 High temperature thermal cutoff device THERM O DISC INC (US) 2013-10-09 EP disclosed
CN-101685733-A High-temperature thermal fuse device THERM O DISC INC 2010-03-31 CN disclosed
EP-2151846-A2 High temperature thermal cutoff device Therm-O-Disc Incorporated (US) 2010-02-10 EP disclosed