Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCRTR1 | O43613 | 2/20 | 0.43 |
| ▸ | HCRTR2 | O43614 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 5/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.38 |
| ▸ | MITF | O75030 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | AR | P10275 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31473132 | 0.79 | HCRTR1 (0.45) | HCRTR1HCRTR2KDM4E | |
| SCHEMBL31473158 | 0.78 | EHMT2 (0.40) | — | |
| SCHEMBL31473150 | 0.76 | HDAC1 (0.40) | KMT2AMEN1LMNASMN1; SMN2MAPT | |
| SCHEMBL31473148 | 0.74 | BRD4 (0.33) | HCRTR1HCRTR2KMT2AMEN1SMN1; SMN2 | |
| SCHEMBL31473167 | 0.74 | MAPT (0.38) | KMT2AMEN1LMNASMN1; SMN2TP53 | |
| SCHEMBL31473141 | 0.70 | CAPN1 (0.35) | — | |
| SCHEMBL13314539 | 0.68 | NPC1 (0.59) | KMT2AMEN1LMNANPC1SMN1; SMN2 | |
| SCHEMBL31473155 | 0.66 | FSHR (0.31) | — | |
| SCHEMBL745146 | 0.64 | HCRTR1 (0.66) | HCRTR1HCRTR2KMT2AMEN1NPC1 | |
| SCHEMBL751322 | 0.63 | HCRTR1 (0.64) | HCRTR1HCRTR2KMT2AMEN1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119403810-A | Compounds, pharmaceutical compositions containing them and their medical use for the treatment or prevention of vascular diseases | 瓦斯塞拉股份有限公司 | 2025-02-07 | — | — | CN | disclosed |