SCHEMBL31473167

SCHEMBL31473167

C[C@H]1C(=O)N(Cc2cccs2)[C@@H](COC(C)(C)C)C(=O)N1C

nearest known ligand 0.38

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
MAPT P10636 6/20 0.38
HSD17B10 Q99714 1/20 0.38
PKM P14618 4/20 0.37
SMN1; SMN2 Q16637 2/20 0.37
ALDH1A1 P00352 6/20 0.37
LMNA P02545 4/20 0.36
TP53 P04637 3/20 0.35
L3MBTL1 Q9Y468 1/20 0.35
KMT2A Q03164 5/20 0.34
MEN1 O00255 4/20 0.34
CYP3A4 P08684 1/20 0.34
CYP2D6 P10635 1/20 0.34
CYP2C9 P11712 1/20 0.34
CYP2C19 P33261 1/20 0.34
KDM4E B2RXH2 2/20 0.34
TDP1 Q9NUW8 1/20 0.34
MAPK1 P28482 1/20 0.33
HTT P42858 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31473158 0.81 EHMT2 (0.40)
SCHEMBL31473150 0.79 HDAC1 (0.40) MAPTPKMSMN1; SMN2ALDH1A1LMNA
SCHEMBL31473148 0.77 BRD4 (0.33) SMN1; SMN2L3MBTL1KMT2AMEN1MAPK1
SCHEMBL31473132 0.76 HCRTR1 (0.45) ALDH1A1KDM4E
SCHEMBL31473141 0.75 CAPN1 (0.35) ALDH1A1
SCHEMBL31473144 0.74 HCRTR1 (0.43) MAPTSMN1; SMN2LMNATP53L3MBTL1
SCHEMBL31473155 0.66 FSHR (0.31)
SCHEMBL31473157 0.63 CYP2C9 (0.32) CYP2C9CYP2C19TDP1
SCHEMBL12403600 0.62 HTT (0.46) MAPTSMN1; SMN2ALDH1A1LMNAL3MBTL1
SCHEMBL14628034 0.61 ALDH1A1 (0.45) MAPTHSD17B10ALDH1A1LMNAL3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260008784-A1 COMPOUNDS, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM AND THEIR MEDICAL USE FOR THE TREATMENT OR PREVENTION OF VASCULAR DISEASES VASTHERA CO LTD (KR) 2026-01-08 US disclosed
CN-119403810-A Compounds, pharmaceutical compositions containing them and their medical use for the treatment or prevention of vascular diseases 瓦斯塞拉股份有限公司 2025-02-07 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260008784-A1 COMPOUNDS, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM AND THEIR MEDICAL USE FOR THE TREATMENT OR PREVENTION OF VASCULAR DISEASES PRDX1, PRDX2, PRDX6 MAPT 4875/4885HSD17B10 891/4885PKM 2806/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.