SCHEMBL31473148

SCHEMBL31473148

Cc1cccc(CN2C(=O)[C@H](C)N(C)C(=O)[C@@H]2COC(C)(C)C)n1

nearest known ligand 0.33

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
BRD4 O60885 1/20 0.33
TLR7 Q9NYK1 1/20 0.31
MAPK1 P28482 4/20 0.31
HCRTR1 O43613 2/20 0.31
HCRTR2 O43614 2/20 0.31
KCNH2 Q12809 2/20 0.31
SCN5A Q14524 1/20 0.31
SCN9A Q15858 1/20 0.31
BCHE P06276 1/20 0.31
ACHE P22303 1/20 0.31
KMT2A Q03164 3/20 0.31
MAPK3 P27361 2/20 0.31
MEN1 O00255 2/20 0.31
OPRM1 P35372 1/20 0.31
OPRD1 P41143 1/20 0.31
CCR9 P51686 1/20 0.30
SMN1; SMN2 Q16637 1/20 0.30
NPSR1 Q6W5P4 1/20 0.30
L3MBTL1 Q9Y468 1/20 0.30
PDE10A Q9Y233 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31473150 0.84 HDAC1 (0.40) MAPK1KMT2AMEN1SMN1; SMN2L3MBTL1
SCHEMBL31473132 0.83 HCRTR1 (0.45) HCRTR1HCRTR2PDE10A
SCHEMBL31473158 0.79 EHMT2 (0.40)
SCHEMBL31473167 0.77 MAPT (0.38) MAPK1KMT2AMEN1SMN1; SMN2L3MBTL1
SCHEMBL31473144 0.74 HCRTR1 (0.43) MAPK1HCRTR1HCRTR2KMT2AMEN1
SCHEMBL31473141 0.70 CAPN1 (0.35)
SCHEMBL31473155 0.65 FSHR (0.31)
SCHEMBL6841102 0.64 MEN1 (0.41) KCNH2KMT2AMEN1OPRM1OPRD1
SCHEMBL31473156 0.64 LMNA (0.37) MAPK1KMT2AMEN1SMN1; SMN2
SCHEMBL31473157 0.64 CYP2C9 (0.32)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260008784-A1 COMPOUNDS, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM AND THEIR MEDICAL USE FOR THE TREATMENT OR PREVENTION OF VASCULAR DISEASES VASTHERA CO LTD (KR) 2026-01-08 US disclosed
CN-119403810-A Compounds, pharmaceutical compositions containing them and their medical use for the treatment or prevention of vascular diseases 瓦斯塞拉股份有限公司 2025-02-07 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260008784-A1 COMPOUNDS, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM AND THEIR MEDICAL USE FOR THE TREATMENT OR PREVENTION OF VASCULAR DISEASES PRDX1, PRDX2, PRDX6 BRD4 3303/4885TLR7 1790/4885MAPK1 2070/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.