Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 4/20 | 0.51 |
| ▸ | GAA | P10253 | 3/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.51 |
| ▸ | NPC1 | O15118 | 2/20 | 0.51 |
| ▸ | MAPT | P10636 | 2/20 | 0.51 |
| ▸ | PKM | P14618 | 2/20 | 0.51 |
| ▸ | IDH1 | O75874 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | EGFR | P00533 | 3/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | ACHE | P22303 | 1/20 | 0.42 |
| ▸ | VNN1 | O95497 | 1/20 | 0.41 |
| ▸ | KCNH3 | Q9ULD8 | 1/20 | 0.40 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.39 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.39 |
| ▸ | ACP3 | P15309 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19205818 | 0.84 | ATP1A1 (0.49) | GAASMN1; SMN2ALDH1A1P2RX3KDM4E | |
| SCHEMBL19205819 | 0.84 | ATP1A1 (0.49) | GAASMN1; SMN2ALDH1A1P2RX3KDM4E | |
| SCHEMBL18483488 | 0.83 | IDH1 (0.45) | GAASMN1; SMN2IDH1ALDH1A1EGFR | |
| SCHEMBL18483484 | 0.83 | IDH1 (0.45) | GAASMN1; SMN2IDH1ALDH1A1EGFR | |
| SCHEMBL18483206 | 0.81 | ALDH1A1 (0.55) | RAB9AGAASMN1; SMN2MAPTIDH1 | |
| SCHEMBL18449481 | 0.81 | ALDH1A1 (0.55) | RAB9AGAASMN1; SMN2MAPTIDH1 | |
| SCHEMBL19205648 | 0.81 | ALDH1A1 (0.55) | RAB9AGAASMN1; SMN2MAPTIDH1 | |
| SCHEMBL11107782 | 0.78 | EGFR (0.47) | RAB9ASMN1; SMN2NPC1MAPTIDH1 | |
| SCHEMBL11108087 | 0.75 | EGFR (0.47) | RAB9ASMN1; SMN2NPC1MAPTIDH1 | |
| SCHEMBL29019896 | 0.75 | ALDH1A1 (0.43) | IDH1ALDH1A1EGFRCA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1511742-B1 | KINASE INHIBITORS | CYTOPIA RES PTY LTD (AU) | 2010-02-03 | — | — | EP | disclosed |