SCHEMBL31473379

SCHEMBL31473379

Cn1c(=O)[nH]c2c(F)c(Br)ccc21

nearest known ligand 0.49

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
RXFP1 Q9HBX9 1/20 0.49
CSNK2A2 P19784 1/20 0.41
CSNK2B P67870 1/20 0.41
CSNK2A1 P68400 1/20 0.41
DAO P14920 4/20 0.38
LMNA P02545 1/20 0.38
BRD4 O60885 3/20 0.36
MAPT P10636 1/20 0.35
PDE2A O00408 2/20 0.34
PDE3B Q13370 2/20 0.34
PDE3A Q14432 2/20 0.34
BRD2 P25440 1/20 0.33
CRBN Q96SW2 1/20 0.32
GPR17 Q13304 1/20 0.32
ADORA3 P0DMS8 1/20 0.32
ADORA2A P29274 1/20 0.32
ADORA2B P29275 1/20 0.32
ADORA1 P30542 1/20 0.32
PGR P06401 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL626494 0.77 RXFP1 (0.43) RXFP1DAOLMNABRD4MAPT
SCHEMBL16739031 0.77 BRD4 (0.51) RXFP1CSNK2A2CSNK2BCSNK2A1DAO
SCHEMBL31473421 0.76 TNKS (0.43) RXFP1DAOLMNABRD4MAPT
SCHEMBL31473360 0.76 RXFP1 (0.42) RXFP1DAOLMNABRD4ADORA2B
SCHEMBL7884503 0.75 RXFP1 (0.47) RXFP1CSNK2A2CSNK2BCSNK2A1DAO
SCHEMBL16738871 0.73 RXFP1 (0.40) RXFP1CSNK2A2CSNK2BCSNK2A1DAO
SCHEMBL25036216 0.72 DAO (0.44) CSNK2A2CSNK2BCSNK2A1DAOLMNA
SCHEMBL24607364 0.72 CSNK2A2 (0.49) RXFP1CSNK2A2CSNK2BCSNK2A1DAO
SCHEMBL1853447 0.71 DAO (0.64) RXFP1DAOLMNAPDE2APDE3B
SCHEMBL16739006 0.71 ALDH1A1 (0.41) RXFP1CSNK2A2CSNK2BCSNK2A1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025096771-A1 MODULATORS OF BCL6 AS LIGAND DIRECTED DEGRADERS BRISTOL-MYERS SQUIBB COMPANY (US) 2025-05-08 WO disclosed
CN-119866333-A KIT inhibitors, compounds, pharmaceutical compositions, and methods of use thereof 亚力维克希斯股份有限公司 2025-04-22 CN disclosed
WO-2025052129-A1 PYRIDINE DERIVATIVES WHICH ACT AS INHIBITORS OF MPTP. NRG THERAPEUTICS LTD (GB) 2025-03-13 WO disclosed