Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | NSD2 | O96028 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | GRM5 | P41594 | 2/20 | 0.35 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | JAK3 | P52333 | 3/20 | 0.34 |
| ▸ | JAK2 | O60674 | 2/20 | 0.34 |
| ▸ | VNN1 | O95497 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | MAOA | P21397 | 1/20 | 0.33 |
| ▸ | MAOB | P27338 | 1/20 | 0.33 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.33 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.33 |
| ▸ | APP | P05067 | 1/20 | 0.33 |
| ▸ | RXRA | P19793 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27295964 | 1.00 | ALDH1A1 (0.37) | ALDH1A1KDM4EL3MBTL1NSD2TP53 | |
| SCHEMBL239037 | 0.84 | SIRT2 (0.42) | ALDH1A1KDM4EL3MBTL1GRM5ABCG2 | |
| SCHEMBL14479223 | 0.81 | APP (0.38) | ALDH1A1TP53JAK3JAK2APP | |
| SCHEMBL2566482 | 0.81 | ALDH1A1 (0.38) | ALDH1A1KDM4EL3MBTL1NSD2TP53 | |
| SCHEMBL27302320 | 0.81 | CYP11B1 (0.36) | ALDH1A1KDM4EL3MBTL1NSD2TP53 | |
| SCHEMBL27303097 | 0.80 | ALDH1A1 (0.40) | ALDH1A1KDM4EL3MBTL1ABCG2JAK3 | |
| SCHEMBL27302925 | 0.80 | GRM5 (0.35) | ALDH1A1KDM4EL3MBTL1GRM5JAK3 | |
| SCHEMBL20173613 | 0.79 | KDM4E (0.48) | ALDH1A1KDM4ENSD2TP53ABCG2 | |
| SCHEMBL30018321 | 0.78 | GBA1 (0.44) | ALDH1A1KDM4EL3MBTL1ABCG2GAA | |
| SCHEMBL31473358 | 0.77 | NSD2 (0.39) | KDM4ENSD2TP53JAK3JAK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119866333-A | KIT inhibitors, compounds, pharmaceutical compositions, and methods of use thereof | 亚力维克希斯股份有限公司 | 2025-04-22 | — | — | CN | disclosed |