Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIRT2 | Q8IXJ6 | 3/20 | 0.42 |
| ▸ | ADK | P55263 | 4/20 | 0.40 |
| ▸ | TMPRSS4 | Q9NRS4 | 1/20 | 0.39 |
| ▸ | MAOA | P21397 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | GRM5 | P41594 | 1/20 | 0.37 |
| ▸ | EGFR | P00533 | 2/20 | 0.35 |
| ▸ | CSF1R | P07333 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.35 |
| ▸ | RXRA | P19793 | 1/20 | 0.34 |
| ▸ | CCR6 | P51684 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27295964 | 0.84 | ALDH1A1 (0.37) | MAOAMAOBKDM4EALDH1A1L3MBTL1 | |
| SCHEMBL31473441 | 0.84 | ALDH1A1 (0.37) | MAOAMAOBKDM4EALDH1A1L3MBTL1 | |
| SCHEMBL27303097 | 0.80 | ALDH1A1 (0.40) | SIRT2KDM4EALDH1A1L3MBTL1ABCG2 | |
| SCHEMBL30018321 | 0.78 | GBA1 (0.44) | ADKMAOAMAOBKDM4EALDH1A1 | |
| SCHEMBL11560142 | 0.77 | KDM4C (0.42) | KDM4EALDH1A1EGFRCSF1RRXRA | |
| SCHEMBL165008 | 0.76 | ALDH1A1 (0.46) | ADKKDM4EALDH1A1L3MBTL1GRM5 | |
| SCHEMBL27308720 | 0.74 | IKBKB (0.33) | KDM4EALDH1A1L3MBTL1ABCG2 | |
| SCHEMBL11560312 | 0.71 | HCAR3 (0.52) | ALDH1A1RXRATSHR | |
| SCHEMBL19418041 | 0.70 | KDM4E (0.42) | KDM4EALDH1A1L3MBTL1HTT | |
| SCHEMBL2815513 | 0.70 | ALDH1A1 (0.41) | SIRT2KDM4EALDH1A1L3MBTL1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120004244-A1 | Bis Aromatic Compounds for Use as LTC4 Synthase Inhibitors | BIOLIPOX AB (SW) | 2012-01-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120004244-A1 | Bis Aromatic Compounds for Use as LTC4 Synthase Inhibitors | LTC4S, LTB4R2, LTB4R | SIRT2 3445/4885ADK 3200/4885TMPRSS4 346/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.