Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 4/20 | 0.47 |
| ▸ | MAOA | P21397 | 1/20 | 0.45 |
| ▸ | GPR174 | Q9BXC1 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | PARP14 | Q460N5 | 1/20 | 0.41 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.41 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | CPS1 | P31327 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8384774 | 0.84 | CA12 (0.57) | MAOBMAOAGPR174MAPK1NPC1 | |
| SCHEMBL12355689 | 0.79 | RARA (0.53) | MAOBMAOARECQL | |
| SCHEMBL25934294 | 0.79 | CRBN (0.47) | MAOBMAOARECQLPARP14PARP10 | |
| SCHEMBL4838140 | 0.79 | MAPT (0.46) | MAOBMAOAPARP14PARP10CPS1 | |
| SCHEMBL25313819 | 0.78 | MAPT (0.45) | MAOBMAOAPARP14PARP10CPS1 | |
| SCHEMBL31747275 | 0.78 | MAOB (0.58) | MAOBMAOAPARP14PARP10NPC1 | |
| Hydrochloric Acid SCHEMBL4838135 | 0.78 | PARP10 (0.45) | MAOBMAOAPARP14PARP10CPS1 | |
| SCHEMBL1554929 | 0.78 | CPS1 (0.61) | MAPK1NPC1CPS1 | |
| SCHEMBL2464487 | 0.78 | MAOB (0.53) | MAOBMAOAGPR174MAPK1TSHR | |
| SCHEMBL12035951 | 0.77 | TSHR (0.42) | MAOBMAOAGPR174MAPK1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025061148-A1 | HETEROARYL COMPOUND, AND PREPARATION METHOD THEREFOR AND USE THEREOF IN MEDICINE | 江苏恒瑞医药股份有限公司 | 2025-03-27 | — | — | WO | disclosed |