Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRBN | Q96SW2 | 1/20 | 0.47 |
| ▸ | KAT6A | Q92794 | 1/20 | 0.47 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.47 |
| ▸ | RARA | P10276 | 1/20 | 0.47 |
| ▸ | RARB | P10826 | 1/20 | 0.47 |
| ▸ | MAOB | P27338 | 5/20 | 0.46 |
| ▸ | MAOA | P21397 | 3/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | PLK1 | P53350 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | PARP14 | Q460N5 | 1/20 | 0.43 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12355689 | 0.94 | RARA (0.53) | CRBNPLA2G2ARARARARBMAOB | |
| SCHEMBL14261935 | 0.90 | MAOA (0.58) | CRBNRARARARBMAOBMAOA | |
| SCHEMBL4838140 | 0.88 | MAPT (0.46) | CRBNMAOBMAOAMAPTPARP14 | |
| SCHEMBL25313819 | 0.87 | MAPT (0.45) | CRBNMAOBMAOAMAPTKMT2A | |
| Hydrochloric Acid SCHEMBL4838135 | 0.87 | PARP10 (0.45) | CRBNMAOBMAOAMAPTPARP14 | |
| SCHEMBL18199320 | 0.86 | PLA2G2A (0.50) | KAT6APLA2G2AMAOBMAOAMAPT | |
| SCHEMBL28519834 | 0.84 | TDP1 (0.51) | PLA2G2AMAOBMAOAMAPTPLK1 | |
| SCHEMBL3874777 | 0.84 | RARA (0.63) | KAT6ARARARARBMAOBMAOA | |
| SCHEMBL21202180 | 0.84 | KDM4E (0.50) | MAOBSMN1; SMN2 | |
| SCHEMBL4566999 | 0.83 | CA12 (0.60) | PLA2G2AMAOBMAOAMAPTNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023141432-A2 | APOL1 INHIBITORS AND METHODS OF USE | MAZE THERAPEUTICS, INC. (US) | 2023-07-27 | — | — | WO | disclosed |