Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC9A1 | P19634 | 1/20 | 0.48 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.48 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | GRM2 | Q14416 | 4/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | HTR3A | P46098 | 1/20 | 0.36 |
| ▸ | ELANE | P08246 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | FBP1 | P09467 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4635179 | 1.00 | SLC9A1 (0.48) | SLC9A1KEAP1TLR8KDM4ELMNA | |
| SCHEMBL30036706 | 0.78 | SLC9A1 (0.50) | SLC9A1KEAP1TLR8KDM4ELMNA | |
| SCHEMBL256210 | 0.78 | SLC9A1 (0.50) | SLC9A1KEAP1TLR8KDM4ELMNA | |
| SCHEMBL3806194 | 0.78 | CYP3A4 (0.50) | TLR8KDM4ETSHRGRM2HSD17B10 | |
| SCHEMBL19008532 | 0.77 | SLC9A1 (0.46) | SLC9A1KEAP1KDM4ELMNATSHR | |
| SCHEMBL9534063 | 0.76 | SLC9A1 (0.39) | SLC9A1KEAP1KDM4ELMNATSHR | |
| SCHEMBL1965207 | 0.76 | SLC9A1 (0.48) | SLC9A1KEAP1KDM4ELMNATSHR | |
| SCHEMBL30929215 | 0.76 | GRM2 (0.62) | SLC9A1KEAP1GRM2 | |
| SCHEMBL10734042 | 0.76 | SLC9A1 (0.48) | SLC9A1KEAP1TLR8KDM4ELMNA | |
| SCHEMBL564689 | 0.76 | POLB (0.48) | TLR8KDM4ELMNATSHRGRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119604512-A | TYK2 inhibitor and application thereof | 阿鲁米斯股份有限公司 | 2025-03-11 | — | — | CN | disclosed |