Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC9A1 | P19634 | 1/20 | 0.48 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.48 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | GRM2 | Q14416 | 4/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | HTR3A | P46098 | 1/20 | 0.36 |
| ▸ | ELANE | P08246 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | FBP1 | P09467 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31474375 | 1.00 | SLC9A1 (0.48) | SLC9A1KEAP1TLR8KDM4ELMNA | |
| SCHEMBL30036706 | 0.78 | SLC9A1 (0.50) | SLC9A1KEAP1TLR8KDM4ELMNA | |
| SCHEMBL256210 | 0.78 | SLC9A1 (0.50) | SLC9A1KEAP1TLR8KDM4ELMNA | |
| SCHEMBL3806194 | 0.78 | CYP3A4 (0.50) | TLR8KDM4ETSHRGRM2HSD17B10 | |
| SCHEMBL19008532 | 0.77 | SLC9A1 (0.46) | SLC9A1KEAP1KDM4ELMNATSHR | |
| SCHEMBL9534063 | 0.76 | SLC9A1 (0.39) | SLC9A1KEAP1KDM4ELMNATSHR | |
| SCHEMBL1965207 | 0.76 | SLC9A1 (0.48) | SLC9A1KEAP1KDM4ELMNATSHR | |
| SCHEMBL30929215 | 0.76 | GRM2 (0.62) | SLC9A1KEAP1GRM2 | |
| SCHEMBL10734042 | 0.76 | SLC9A1 (0.48) | SLC9A1KEAP1TLR8KDM4ELMNA | |
| SCHEMBL564689 | 0.76 | POLB (0.48) | TLR8KDM4ELMNATSHRGRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6938999-B2 | Water base ink for ink-jet recording | BROTHER KOGYO KABUSHIKI KAISHA (JP) | 2005-09-06 | — | — | US | claimed |
| US-20040031417-A1 | Water base ink for ink-jet recording | BROTHER KOGYO KABUSHIKI KAISHA (JP) | 2004-02-19 | — | — | US | claimed |
| US-6648463-B2 | Printer with nickel metal or alloy head and ink containing benzotriazole based metal inactivating agent and alkanolamine limiting corrosion; stable, long term jetting operation | BROTHER KOGYO KABUSHIKI KAISHA (JP) | 2003-11-18 | — | — | US | claimed |
| US-20030067524-A1 | Water base ink for ink-jet recording | BROTHER KOGYO KABUSHIKI KAISHA (JP) | 2003-04-10 | — | — | US | claimed |
| US-20240239801-A1 | PYRIMIDO[5,4,D]PYRIMIDINE COMPOUNDS, COMPOSITIONS COMPRISING THEM AND USES THEREOF | Université de Montréal (CA) | 2024-07-18 | — | — | US | disclosed |
| US-20240239801-A1 | PYRIMIDO[5,4,D]PYRIMIDINE COMPOUNDS, COMPOSITIONS COMPRISING THEM AND USES THEREOF | Université de Montréal (CA) | 2024-07-18 | — | — | US | disclosed |
| US-20240217971-A1 | PYRIDO[3,2-D]PYRIMIDINE COMPOUNDS USES THEREOF FOR TREATING A PROLIFERATIVE DISEASE | Université de Montréal (CA) | 2024-07-04 | — | — | US | disclosed |
| WO-2024077391-A1 | THIAZOLO[5,4-D]PYRIMIDINE COMPOUNDS, COMPOSITIONS COMPRISING THEM AND USES THEREOF | UNIVERSITE DE MONTREAL (CA) | 2024-04-18 | — | — | WO | disclosed |
| EP-3467930-B1 | NONAQUEOUS ELECTROLYTE AND NONAQUEOUS SECONDARY BATTERY | ASAHI CHEMICAL IND (JP) | 2020-05-13 | — | — | EP | disclosed |
| EP-3467930-A1 | NONAQUEOUS ELECTROLYTE AND NONAQUEOUS SECONDARY BATTERY | ASAHI KASEI KABUSHIKI KAISHA (JP) | 2019-04-10 | — | — | EP | disclosed |
| US-10037894-B2 | Polishing liquid for metal and polishing method | HITACHI CHEMICAL COMPANY, LTD. (JP) | 2018-07-31 | — | — | US | disclosed |
| EP-3279997-A1 | NONAQUEOUS ELECTROLYTE AND NONAQUEOUS SECONDARY BATTERY | Asahi Kasei Kabushiki Kaisha (JP) | 2018-02-07 | — | — | EP | disclosed |
| US-20140370707-A1 | POLISHING LIQUID FOR METAL AND POLISHING METHOD | RESONAC CORPORATION (JP) | 2014-12-18 | — | — | US | disclosed |
| EP-1607455-B1 | Water base ink for ink-jet recording | BROTHER IND LTD (JP) | 2008-06-11 | — | — | EP | disclosed |
| EP-1607455-A1 | Water base ink for ink-jet recording | BROTHER KOGYO KABUSHIKI KAISHA (JP) | 2005-12-21 | — | — | EP | disclosed |
| US-20050275701-A1 | Water base ink for ink-jet recording | BROTHER KOGYO KABUSHIKI KAISHA (JP) | 2005-12-15 | — | — | US | disclosed |
| US-6938999-B2 | Water base ink for ink-jet recording | BROTHER KOGYO KABUSHIKI KAISHA (JP) | 2005-09-06 | — | — | US | disclosed |
| US-20040031417-A1 | Water base ink for ink-jet recording | BROTHER KOGYO KABUSHIKI KAISHA (JP) | 2004-02-19 | — | — | US | disclosed |
| US-6648463-B2 | Printer with nickel metal or alloy head and ink containing benzotriazole based metal inactivating agent and alkanolamine limiting corrosion; stable, long term jetting operation | BROTHER KOGYO KABUSHIKI KAISHA (JP) | 2003-11-18 | — | — | US | disclosed |
| US-20030067524-A1 | Water base ink for ink-jet recording | BROTHER KOGYO KABUSHIKI KAISHA (JP) | 2003-04-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240239801-A1 | PYRIMIDO[5,4,D]PYRIMIDINE COMPOUNDS, COMPOSITIONS COMPRISING THEM AND USES THEREOF | NRAS, BRAF, KRAS | SLC9A1 2512/4885KEAP1 3052/4885TLR8 2947/4885 |
| US-20240217971-A1 | PYRIDO[3,2-D]PYRIMIDINE COMPOUNDS USES THEREOF FOR TREATING A PROLIFERATIVE DISEASE | BRAF, NRAS, DPYD | SLC9A1 2393/4885KEAP1 2880/4885TLR8 3213/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.