Known targets — ChEMBL curated mechanism
ACHECHKACHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNB1CHRNDCHRNECHRNGHRH2OPRM1
The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | TYR | P14679 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Fluoride Ion SCHEMBL6306829 | 0.97 | ALDH1A1 (0.34) | ALDH1A1CA2POLBTYRSMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL3154711 | 0.97 | ALDH1A1 (0.34) | ALDH1A1CA2POLBTYRSMN1; SMN2 | |
| Iodide SCHEMBL3156624 | 0.97 | ALDH1A1 (0.34) | ALDH1A1CA2POLBTYRSMN1; SMN2 | |
| Bromide SCHEMBL6304580 | 0.88 | — | — | |
| Bromide SCHEMBL6311960 | 0.85 | CA1 (0.40) | CA2 | |
| Fluoride Ion SCHEMBL6311932 | 0.85 | — | — | |
| Iodide SCHEMBL6304877 | 0.85 | — | — | |
| Hydrochloric Acid SCHEMBL6306871 | 0.85 | — | — | |
| Bromide SCHEMBL6312692 | 0.83 | CA2 (0.32) | ALDH1A1CA2 | |
| Iodide SCHEMBL6307731 | 0.82 | CA1 (0.40) | CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6951906-B1 | Process for hydrogenating a conjugated diene polymer | KOREA KUMHO PETROCHEMICAL CO., LTD. (KR) | 2005-10-04 | — | — | US | claimed |
| EP-1124863-B1 | PROCESS FOR HYDROGENATING A CONJUGATED DIENE POLYMER | KOREA KUMHO PETROCHEM CO LTD (KR) | 2004-07-21 | — | — | EP | claimed |
| EP-1124863-A1 | PROCESS FOR HYDROGENATING A CONJUGATED DIENE POLYMER | Korea Kumho Petrochemical Co. Ltd. (KR) | 2001-08-22 | — | — | EP | claimed |
| WO-2000008069-A1 | PROCESS FOR HYDROGENATING A CONJUGATED DIENE POLYMER | KOREA KUMHO PETROCHEMICAL CO., LTD. (KR) | 2000-02-17 | — | — | WO | claimed |
| EP-1435362-B1 | Process for polymer hydrogenation using lithium hydride prepared from reactor equipped with high-speed injection nozzle | KOREA KUMHO PETROCHEM CO LTD (KR) | 2010-03-03 | — | — | EP | disclosed |
| US-6951906-B1 | Process for hydrogenating a conjugated diene polymer | KOREA KUMHO PETROCHEMICAL CO., LTD. (KR) | 2005-10-04 | — | — | US | disclosed |
| US-6864326-B2 | Process for polymer hydrogenation using lithium hydride prepared from reactor equipped with high-speed injection nozzle | KOREA KUMHO PETROCHEMICAL CO., LTD. (KR) | 2005-03-08 | — | — | US | disclosed |
| EP-1124863-B1 | PROCESS FOR HYDROGENATING A CONJUGATED DIENE POLYMER | KOREA KUMHO PETROCHEM CO LTD (KR) | 2004-07-21 | — | — | EP | disclosed |
| US-20040132916-A1 | Process for polymer hydrogenation using lithium hydride prepared from reactor equipped with high-speed injection nozzle | KOREA KUMHO PETROCHEMICAL CO., LTD. | 2004-07-08 | — | — | US | disclosed |
| EP-1435362-A1 | Process for polymer hydrogenation using lithium hydride prepared from reactor equipped with high-speed injection nozzle | Korea Kumho Petrochemical Co. Ltd. (KR) | 2004-07-07 | — | — | EP | disclosed |
| EP-1124863-A1 | PROCESS FOR HYDROGENATING A CONJUGATED DIENE POLYMER | Korea Kumho Petrochemical Co. Ltd. (KR) | 2001-08-22 | — | — | EP | disclosed |
| WO-2000008069-A1 | PROCESS FOR HYDROGENATING A CONJUGATED DIENE POLYMER | KOREA KUMHO PETROCHEMICAL CO., LTD. (KR) | 2000-02-17 | — | — | WO | disclosed |