SCHEMBL3147475

SCHEMBL3147475

NC(=O)C1=NC(=O)N=C1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2160930 0.80
SCHEMBL10713236 0.78
SCHEMBL27818666 0.76
SCHEMBL10808985 0.69 HSD17B3 (0.37)
SCHEMBL3005157 0.67 HTT (0.34)
SCHEMBL5346010 0.67 PEPD (0.33)
SCHEMBL10501116 0.66 KMT2A (0.55)
SCHEMBL3009265 0.64 CCNC (0.34)
SCHEMBL1693134 0.64
SCHEMBL16497484 0.62

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-53090262-A None JP disclosed
US-11618765-B2 Broad-spectrum antiviral nucleoside derivatives KALMAN THOMAS I (US) 2023-04-04 US disclosed
EP-1835035-B1 A process for immobilizing cells on a resin EXPLORA LAB SA (CH) 2010-02-17 EP disclosed
US-20070249023-A1 Process for immobilizing cells on a resin EXPLORA LABORATORIES S.A. (CH) 2007-10-25 US disclosed
EP-1835035-A1 A process for immobilizing cells on a resin EXPLORA Laboratories SA (CH) 2007-09-19 EP disclosed
EP-0078546-B1 NOVEL IMIDAZOLECARBOXAMIDE DERIVATIVES MERRELL DOW PHARMACEUTICALS INC. (US) 1986-11-12 EP disclosed
EP-0078546-A1 Novel imidazolecarboxamide derivatives MERRELL DOW PHARMACEUTICALS INC. (US) 1983-05-11 EP disclosed
JP-S5390262-A IMIDAZOLONECARBOXAMIDE DERIVS. TAKEDA CHEM IND LTD 1978-08-08 JP disclosed