SCHEMBL5346010

SCHEMBL5346010

NC(=O)NC1=NC(=O)N=C1

nearest known ligand 0.33

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
PEPD P12955 1/20 0.33
NPC1 O15118 1/20 0.32
ALDH1A1 P00352 1/20 0.32
GAA P10253 1/20 0.31
MAPT P10636 1/20 0.31
GFER P55789 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9563901 0.73
SCHEMBL3147475 0.67
SCHEMBL3005157 0.62 HTT (0.34)
SCHEMBL2395708 0.61 HSD17B10 (0.42) NPC1ALDH1A1GAAMAPTGFER
SCHEMBL3009265 0.60 CCNC (0.34)
SCHEMBL1693134 0.59
SCHEMBL230957 0.58 MDM2 (0.67) PEPDNPC1ALDH1A1GAAMAPT
Hydrochloric Acid SCHEMBL27714679 0.57 MDM2 (0.64) PEPDNPC1ALDH1A1GAAMAPT
SCHEMBL9505940 0.57 PEPD (0.40) PEPDNPC1ALDH1A1GAAMAPT
SCHEMBL515345 0.56 CYP1A2 (0.42) PEPDNPC1ALDH1A1GAAMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1492762-B1 PHOTOSTABLE CATIONIC ORGANIC SUNSCREEN COMPOUNDS WITH ANTIOXIDANT PROPERTIES AND COMPISITIONS OBTAINED THEREFROM MERCK PATENT GMBH (DE) 2007-11-14 EP disclosed
US-6936735-B2 Photostable cationic organic sunscreen compounds and compositions obtained therefrom EMD CHEMICALS, INC. (US) 2005-08-30 US disclosed
US-6699463-B2 Photostable cationic organic sunscreen compounds with antioxidant properties and compositions obtained therefrom EM INDUSTRIES 2004-03-02 US disclosed