SCHEMBL31474902

SCHEMBL31474902

CCCC[Sn](CCCC)(CCCC)c1cccc(C(=O)ON2C(=O)CCC2=O)c1

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPK1 P28482 1/20 0.35
GRM2 Q14416 1/20 0.34
KMT2A Q03164 3/20 0.33
SMN1; SMN2 Q16637 3/20 0.33
NPC1 O15118 1/20 0.33
CYP1A2 P05177 1/20 0.33
CYP2C9 P11712 1/20 0.33
HPGD P15428 1/20 0.33
CYP2C19 P33261 1/20 0.33
RAB9A P51151 1/20 0.33
ALOX5 P09917 1/20 0.33
MGLL Q99685 1/20 0.32
POLB P06746 1/20 0.32
ALDH1A1 P00352 1/20 0.32
HSD17B10 Q99714 1/20 0.32
CYP4F2 P78329 1/20 0.32
CYP4A11 Q02928 1/20 0.32
MAPT P10636 2/20 0.32
NPSR1 Q6W5P4 1/20 0.32
RXFP1 Q9HBX9 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31474901 1.00 MAPK1 (0.35) MAPK1GRM2KMT2ASMN1; SMN2NPC1
SCHEMBL317623 1.00 MAPK1 (0.35) MAPK1GRM2KMT2ASMN1; SMN2NPC1
SCHEMBL31474903 1.00 MAPK1 (0.35) MAPK1GRM2KMT2ASMN1; SMN2NPC1
SCHEMBL23646860 0.88 ESR1 (0.32) KMT2ASMN1; SMN2CYP1A2CYP2C19ALDH1A1
SCHEMBL318285 0.85 KMT2A (0.36) MAPK1GRM2KMT2ASMN1; SMN2NPC1
Bromide SCHEMBL16897747 0.83 MEN1 (0.38) KMT2ASMN1; SMN2
SCHEMBL9349704 0.82 CYP2C9 (0.34) CYP2C9CYP2C19MAPT
SCHEMBL334846 0.81 MAPK1 (0.40) MAPK1KMT2ASMN1; SMN2NPC1CYP1A2
SCHEMBL29935686 0.80 HTR7 (0.33) GRM2KMT2ASMN1; SMN2HPGDMGLL
SCHEMBL3874638 0.79 THRB (0.34) KMT2ASMN1; SMN2NPC1HPGDRAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025122976-A1 B7-H3 MINIPROTEINS, CONJUGATES, AND USES THEREOF AKTIS ONCOLOGY, INC. (US) 2025-06-12 WO claimed
WO-2025072791-A2 MINIPROTEINS, CONJUGATES & USES THEREOF AKTIS ONCOLOGY, INC. (US) 2025-04-03 WO claimed
WO-2025122976-A1 B7-H3 MINIPROTEINS, CONJUGATES, AND USES THEREOF AKTIS ONCOLOGY, INC. (US) 2025-06-12 WO disclosed
WO-2025072791-A2 MINIPROTEINS, CONJUGATES & USES THEREOF AKTIS ONCOLOGY, INC. (US) 2025-04-03 WO disclosed