SCHEMBL31475403

SCHEMBL31475403

O=c1c(Cl)cc2cnc(Cl)nc2n1C1CCCC1

nearest known ligand 0.57

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
CDK2 P24941 18/20 0.57
CCND1 P24385 18/20 0.57
CCNE1 P24864 17/20 0.57
CDK6 Q00534 16/20 0.57
CDK4 P11802 5/20 0.57
CCND3 P30281 3/20 0.57
CCNT1 O60563 3/20 0.57
CDK9 P50750 3/20 0.57
CCNA2 P20248 1/20 0.46
CCND2 P30279 1/20 0.43
NUAK1 O60285 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27361409 0.85 CCND1 (0.54) CDK2CCND1CCNE1CDK6CDK4
SCHEMBL27361395 0.83 CDK2 (0.55) CDK2CCND1CCNE1CDK6CDK4
SCHEMBL22860084 0.83 NUAK1 (0.59) CDK2CCND1CCNE1CDK6CDK4
SCHEMBL25123123 0.82 CCNE1 (0.62) CDK2CCND1CCNE1CDK6CDK4
SCHEMBL30836981 0.82 CCNE1 (0.62) CDK2CCND1CCNE1CDK6CDK4
SCHEMBL20676931 0.79 CCND1 (0.42) CDK2CCND1CCNE1CDK6CDK4
SCHEMBL4189989 0.79 CCNT1 (0.42) CDK2CCND1CCNE1CDK6CDK4
SCHEMBL1993255 0.79 CTSK (0.41) CDK2CCND1CCNE1CDK6CDK4
SCHEMBL6807554 0.78 CCND1 (0.60) CDK2CCND1CCNE1CDK6CDK4
SCHEMBL22174830 0.78 CDK4 (0.49) CDK2CCND1CCNE1CDK6CDK4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119715833-A Method for detecting related substances in par Bai Xi or salt thereof 北京斯利安药业有限公司 2025-03-28 CN claimed
CN-119715833-A Method for detecting related substances in par Bai Xi or salt thereof 北京斯利安药业有限公司 2025-03-28 CN disclosed