SCHEMBL31475640

SCHEMBL31475640

CC(C)(C)c1sc(S(N)(=O)=O)c(F)c1C(C)(C)O

nearest known ligand 0.33

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
PTGS2 P35354 2/20 0.33
PTGS1 P23219 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31475632 0.71 CA1 (0.31)
SCHEMBL21962321 0.63 PTGS2 (0.33) PTGS2PTGS1
SCHEMBL20698783 0.63 PTGS2 (0.48) PTGS2PTGS1
SCHEMBL22020696 0.62 PTGS2 (0.38) PTGS2PTGS1
SCHEMBL21962637 0.61 ALDH1A1 (0.31)
SCHEMBL18802744 0.60 MEN1 (0.38)
SCHEMBL18802776 0.60 MEN1 (0.33)
SCHEMBL19475024 0.58 APEX1 (0.45) PTGS2PTGS1
SCHEMBL18802742 0.57 MEN1 (0.32)
SCHEMBL14138099 0.57 KMT2A (0.31)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113166065-B Compounds and compositions for treating disorders associated with NLRP activity 诺华股份有限公司 2025-04-15 CN disclosed