Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 10/20 | 0.44 |
| ▸ | HRH2 | P25021 | 5/20 | 0.44 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21963095 | 1.00 | HRH3 (0.44) | HRH3HRH2PDE10A | |
| SCHEMBL22019710 | 0.84 | HRH2 (0.40) | HRH3HRH2PDE10A | |
| SCHEMBL24978304 | 0.83 | HRH3 (0.44) | HRH3HRH2 | |
| SCHEMBL21963378 | 0.81 | HRH3 (0.43) | HRH3HRH2 | |
| SCHEMBL21963073 | 0.79 | PDE10A (0.41) | HRH3HRH2PDE10A | |
| SCHEMBL22282198 | 0.77 | HRH3 (0.38) | HRH3HRH2 | |
| SCHEMBL24977997 | 0.77 | HRH2 (0.36) | HRH3HRH2 | |
| SCHEMBL21963361 | 0.76 | HRH3 (0.35) | HRH3HRH2 | |
| SCHEMBL22010279 | 0.72 | ACHE (0.50) | HRH3HRH2 | |
| SCHEMBL30120755 | 0.72 | ACHE (0.50) | HRH3HRH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113166065-B | Compounds and compositions for treating disorders associated with NLRP activity | 诺华股份有限公司 | 2025-04-15 | — | — | CN | disclosed |