SCHEMBL31475644

SCHEMBL31475644

CC(C)(C)[Si](C)(C)OCc1nc(S(N)(=O)=O)sc1[Si](C)(C)C(C)(C)C

nearest known ligand 0.33

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
CA2 P00918 7/20 0.33
CA12 O43570 2/20 0.30
CA1 P00915 2/20 0.30
CA9 Q16790 2/20 0.30
CA14 Q9ULX7 2/20 0.30
KDM4E B2RXH2 1/20 0.30
LMNA P02545 1/20 0.30
CA3 P07451 1/20 0.30
PKM P14618 1/20 0.30
CA4 P22748 1/20 0.30
CA6 P23280 1/20 0.30
CA5A P35218 1/20 0.30
CA7 P43166 1/20 0.30
KMT2A Q03164 1/20 0.30
HIF1A Q16665 1/20 0.30
CA13 Q8N1Q1 1/20 0.30
TDP1 Q9NUW8 1/20 0.30
CA5B Q9Y2D0 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29764179 0.73 CA2 (0.35) CA2CA12CA1CA9CA14
SCHEMBL22020703 0.71 CA2 (0.36) CA2CA12CA1CA9CA14
SCHEMBL22020320 0.70 CA2 (0.40) CA2CA12CA1CA9CA14
SCHEMBL20681230 0.70 CA2 (0.33) CA2CA12CA1CA9CA14
SCHEMBL22020705 0.69 CA2 (0.33) CA2
SCHEMBL21962112 0.68
SCHEMBL24978527 0.68 CA2 (0.32) CA2
SCHEMBL21962387 0.68 CA2 (0.32) CA2
SCHEMBL21962381 0.68 CA2 (0.32) CA2
SCHEMBL23319822 0.66 CA2 (0.32) CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113166065-B Compounds and compositions for treating disorders associated with NLRP activity 诺华股份有限公司 2025-04-15 CN disclosed