Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 5/20 | 0.40 |
| ▸ | CA12 | O43570 | 2/20 | 0.34 |
| ▸ | CA1 | P00915 | 2/20 | 0.34 |
| ▸ | CA9 | Q16790 | 2/20 | 0.34 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 2/20 | 0.30 |
| ▸ | RAB9A | P51151 | 2/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21962064 | 0.81 | CA2 (0.31) | CA2 | |
| SCHEMBL3600443 | 0.76 | SMN1; SMN2 (0.50) | NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL31169393 | 0.76 | CA2 (0.32) | CA2 | |
| SCHEMBL3196805 | 0.74 | CA2 (0.32) | CA2NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL5884292 | 0.74 | SLC6A3 (0.35) | NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL22021469 | 0.74 | PKM (0.41) | NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL20929927 | 0.74 | CA2 (0.36) | CA2CA12CA1CA9CA14 | |
| SCHEMBL4902324 | 0.73 | ALDH1A1 (0.38) | CA2NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL531672 | 0.73 | NPC1 (0.30) | NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL31282934 | 0.73 | ALDH1A1 (0.32) | NPC1RAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020102096-A1 | COMPOUNDS AND COMPOSITIONS FOR TREATING CONDITIONS ASSOCIATED WITH NLRP ACTIVITY | NOVARTIS INFLAMMASOME RESEARCH, INC. (US) | 2020-05-22 | — | — | WO | disclosed |
| US-20160248025-A1 | Organic Electroluminescent Device | UDC IRELAND LTD (IE) | 2016-08-25 | — | — | US | disclosed |