Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.34 |
| ▸ | HRH2 | P25021 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | POLB | P06746 | 2/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.32 |
| ▸ | ACHE | P22303 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | CASP1 | P29466 | 1/20 | 0.32 |
| ▸ | CASP7 | P55210 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | USP2 | O75604 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21963393 | 0.85 | GAA (0.35) | GAACYP1A2KDM4EMAPTMEN1 | |
| SCHEMBL21963178 | 0.81 | ACHE (0.45) | GAACYP1A2KDM4EMAPTMEN1 | |
| SCHEMBL22021099 | 0.77 | NLRP3 (0.48) | GAACYP1A2NLRP3KDM4EMAPT | |
| SCHEMBL22021144 | 0.77 | NLRP3 (0.48) | GAACYP1A2NLRP3KDM4EMAPT | |
| SCHEMBL22019742 | 0.74 | CYP1A2 (0.36) | GAACYP1A2NLRP3KDM4EMAPT | |
| SCHEMBL24979122 | 0.73 | ACHE (0.55) | KDM4EHRH3HRH2MEN1KMT2A | |
| SCHEMBL21962895 | 0.73 | ACHE (0.55) | KDM4EHRH3HRH2MEN1KMT2A | |
| SCHEMBL21962929 | 0.73 | ACHE (0.55) | KDM4EHRH3HRH2MEN1KMT2A | |
| SCHEMBL30162092 | 0.73 | ACHE (0.55) | KDM4EHRH3HRH2MEN1KMT2A | |
| SCHEMBL30120762 | 0.73 | ACHE (0.55) | KDM4EHRH3HRH2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113166065-B | Compounds and compositions for treating disorders associated with NLRP activity | 诺华股份有限公司 | 2025-04-15 | — | — | CN | disclosed |