⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2010304 | 0.80 | HPGD (0.41) | — | |
| SCHEMBL2972 | 0.72 | — | — | |
| SCHEMBL22115865 | 0.72 | — | — | |
| SCHEMBL135028 | 0.72 | — | — | |
| SCHEMBL9988099 | 0.69 | TRPA1 (0.37) | — | |
| SCHEMBL1633732 | 0.69 | — | — | |
| SCHEMBL4838369 | 0.69 | — | — | |
| SCHEMBL6652755 | 0.69 | — | — | |
| SCHEMBL3231091 | 0.69 | ALDH1A1 (0.43) | — | |
| SCHEMBL1099203 | 0.69 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 330 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024137671-A1 | COMPOUNDS THAT INHIBIT PKMYT1 | EXELIXIS, INC. (US) | 2024-06-27 | — | — | WO | claimed |
| CN-115725110-B | Silicone resin modified polybenzoxazine aerogel and preparation method thereof | 航天特种材料及工艺技术研究所 | 2024-03-26 | — | — | CN | claimed |
| US-20220153713-A1 | HYDRAZONE AMIDE DERIVATIVE AND APPLICATION THEREOF IN PREPARATION OF MEDICAMENTS FOR PREVENTING AND TREATING ALOPECIA | SHENZHEN CELL INSPIRE PHARMACEUTICAL DEVELOPMENT CO., LTD. (CN) | 2022-05-19 | — | — | US | claimed |
| US-20220153688-A1 | HYDRAZONE AMIDE DERIVATIVES AND USE THEREOF IN PREPARATION OF ANTI-OSTEOPOROSIS DRUGS | SHENZHEN CELL INSPIRE PHARMACEUTICAL DEVELOPMENT CO., LTD. (CN) | 2022-05-19 | — | — | US | claimed |
| EP-3992184-A1 | HYDRAZONE AMIDE DERIVATIVES AND USE THEREOF IN PREPARATION OF ANTI-OSTEOPOROSIS DRUGS | Shenzhen Cell Inspire Pharmaceutical Development Co., Ltd. (CN) | 2022-05-04 | — | — | EP | claimed |
| EP-3992185-A1 | HYDRAZONE AMIDE DERIVATIVE AND APPLICATION THEREOF IN PREPARATION OF MEDICAMENTS FOR PREVENTING AND TREATING ALOPECIA | Shenzhen Cell Inspire Pharmaceutical Development Co., Ltd. (CN) | 2022-05-04 | — | — | EP | claimed |
| CN-113214342-A | 23-hydroxy betulinic acid 3-site modified derivative, preparation method and application | 中国药科大学 | 2021-08-06 | — | — | CN | claimed |
| CN-107974080-B | Polyamide moulding compositions and multilayer structures made therefrom | EMS专利股份公司 | 2021-07-20 | — | — | CN | claimed |
| CN-113121517-A | Triazole derivative and preparation method and application thereof | 中山大学 | 2021-07-16 | — | — | CN | claimed |
| CN-113105411-A | Hydrazone amide derivatives and pharmaceutical compositions | 深圳市三启药物开发有限公司 | 2021-07-13 | — | — | CN | claimed |
| US-5968942-A | INHIBITORS OF HIV PROTEASE | G. D. SEARLE & CO. (US) | 1999-10-19 | — | — | US | claimed |
| EP-0715618-B1 | HYDROXYETHYLAMINO SULPHONAMIDES USEFUL AS RETROVIRAL PROTEASE INHIBITORS | SEARLE & CO (US) | 1998-12-16 | — | — | EP | claimed |
| EP-0715618-A1 | HYDROXYETHYLAMINO SULPHONAMIDES USEFUL AS RETROVIRAL PROTEASE INHIBITORS | G.D. SEARLE & CO. (US) | 1996-06-12 | — | — | EP | claimed |
| WO-1995006030-A1 | HYDROXYETHYLAMINO SULPHONAMIDES USEFUL AS RETROVIRAL PROTEASE INHIBITORS | G.D. SEARLE & CO. (US) | 1995-03-02 | — | — | WO | claimed |
| US-5160504-A | Colorfastness to rubbing and light, metal-tanned leather | ORIENT CHEMICAL INDUSTRIES, LTD. (JP) | 1992-11-03 | — | — | US | claimed |
| US-5095100-A | Metal complex dyes and preparation thereof | ORIENT CHEMICAL INDUSTRIES, LTD. (JP) | 1992-03-10 | — | — | US | claimed |
| US-5010099-A | Immunomodulation; antitumor agents | HARBOR BRANCH OCEANOGRAPHIC INSTITUTION, INC. (US) | 1991-04-23 | — | — | US | claimed |
| US-4939168-A | Discodermolide compounds, compositions containing same and methods of preparation and use | HARBOR BRANCH OCEANOGRAPHICS INSTITUTION, INC. (US) | 1990-07-03 | — | — | US | claimed |
| US-H726-H | HAIR DYES | CLAIROL INCORPORATED (US) | 1990-01-02 | — | — | US | claimed |
| US-4009156-A | Hydroxynaphthalene trisazo dyestuffs | BAYER AKTIENGESELLSCHAFT (DT) | 1977-02-22 | — | — | US | claimed |