Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 1/20 | 0.39 |
| ▸ | NR1H2 | P55055 | 2/20 | 0.37 |
| ▸ | NR1H3 | Q13133 | 2/20 | 0.37 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | BRS3 | P32247 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | PPARG | P37231 | 1/20 | 0.35 |
| ▸ | PPARA | Q07869 | 1/20 | 0.35 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31476883 | 0.96 | PARP1 (0.38) | PARP1NR1H2NR1H3L3MBTL1MAPK1 | |
| SCHEMBL31476843 | 0.95 | L3MBTL1 (0.38) | PARP1NR1H2NR1H3L3MBTL1MAPK1 | |
| SCHEMBL31218714 | 0.83 | KDM4E (0.45) | PARP1CHEK2KDM4EALDH1A1LMNA | |
| SCHEMBL4844436 | 0.82 | PARP1 (0.46) | PARP1NR1H2NR1H3CHEK2ALDH1A1 | |
| SCHEMBL4844424 | 0.82 | PARP1 (0.46) | PARP1NR1H2NR1H3CHEK2ALDH1A1 | |
| SCHEMBL8116046 | 0.80 | CHEK2 (0.44) | PARP1NR1H2CHEK2KDM4EALDH1A1 | |
| SCHEMBL874385 | 0.76 | PARP1 (0.48) | PARP1NR1H2NR1H3 | |
| SCHEMBL30696599 | 0.75 | EPHX2 (0.53) | KDM4EALDH1A1GPR119 | |
| SCHEMBL30696664 | 0.75 | HRH2 (0.55) | — | |
| SCHEMBL4710881 | 0.74 | PARP1 (0.48) | PARP1NR1H2NR1H3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119730847-A | NRF2 protein degradation agent | 盖尼米德肿瘤学股份有限公司 | 2025-03-28 | — | — | CN | disclosed |