SCHEMBL3147758

SCHEMBL3147758

CCCCCn1sc2ccccc2c1=O

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
FAAH O00519 1/20 0.97
MGLL Q99685 1/20 0.97
CASP3 P42574 5/20 0.68
KAT2A Q92830 1/20 0.64
KAT2B Q92831 1/20 0.64
G6PD P11413 1/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11185114 0.98 FAAH (1.00) FAAHMGLLCASP3KAT2AKAT2B
SCHEMBL8621525 0.98 FAAH (1.00) FAAHMGLLCASP3KAT2AKAT2B
SCHEMBL1538479 0.98 FAAH (1.00) FAAHMGLLCASP3KAT2AKAT2B
SCHEMBL27971645 0.98 FAAH (1.00) FAAHMGLLCASP3KAT2AKAT2B
SCHEMBL1538488 0.98 FAAH (1.00) FAAHMGLLCASP3KAT2AKAT2B
SCHEMBL24327898 0.98 FAAH (1.00) FAAHMGLLCASP3KAT2AKAT2B
SCHEMBL8621594 0.98 FAAH (1.00) FAAHMGLLCASP3KAT2AKAT2B
SCHEMBL29370720 0.95 FAAH (0.88) FAAHMGLLCASP3KAT2AKAT2B
SCHEMBL203818 0.95 FAAH (0.88) FAAHMGLLCASP3KAT2AKAT2B
SCHEMBL16601156 0.95 FAAH (0.88) FAAHMGLLCASP3KAT2AKAT2B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0026791-B1 2-ARYL-1,2-BENZISOTHIAZOLINONE-1,1-DIOXIDES AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM MERCK & CO. INC. (US) 1984-05-02 EP claimed
EP-0026791-A1 2-Aryl-1,2-benzisothiazolinone-1,1-dioxides and pharmaceutical compositions containing them MERCK & CO. INC. (US) 1981-04-15 EP claimed
CN-113036132-B Polymer composition for nonaqueous secondary battery and nonaqueous secondary battery 旭化成株式会社 2024-06-14 CN disclosed
CN-116529274-A Polymer composition for nonaqueous secondary battery and nonaqueous secondary battery 旭化成株式会社 2023-08-01 CN disclosed
WO-2022202958-A1 NON-AQUEOUS SECONDARY BATTERY POLYMER COMPOSITION AND NON-AQUEOUS SECONDARY BATTERY 旭化成株式会社 2022-09-29 WO disclosed
WO-2022131253-A1 NON-AQUEOUS SECONDARY BATTERY POLYMER COMPOSITION AND NON-AQUEOUS SECONDARY BATTERY 旭化成株式会社 2022-06-23 WO disclosed
WO-2022081984-A1 METHODS AND COMPOUNDS TO TREAT SARS INFECTIONS THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2022-04-21 WO disclosed
CN-113036133-A Polymer composition for nonaqueous secondary battery, and nonaqueous secondary battery 旭化成株式会社 2021-06-25 CN disclosed
CN-113036132-A Polymer composition for nonaqueous secondary battery and nonaqueous secondary battery 旭化成株式会社 2021-06-25 CN disclosed
EP-2110426-B1 METALWORKING FLUID AND METALWORKING METHOD KYODO YUSHI (JP) 2013-10-16 EP disclosed
US-8375755-B2 Metal working fluid composition and metal working method KYODO YUSHI CO., LTD. (JP) 2013-02-19 US disclosed
US-4369183-A 2-Pyridyl-1,2-benzisothiazolinone-1,1-dioxides and their use as selective protease inhibitors MERCK & CO., INC. (US) 1983-01-18 US disclosed
US-4276298-A 2-Aryl-1,2-benzisothiazolinone-1,1-dioxides and their use as selective protease inhibitors MERCK & CO., INC. (US) 1981-06-30 US disclosed
EP-0026791-A1 2-Aryl-1,2-benzisothiazolinone-1,1-dioxides and pharmaceutical compositions containing them MERCK & CO. INC. (US) 1981-04-15 EP disclosed
EP-0026791-A1 2-Aryl-1,2-benzisothiazolinone-1,1-dioxides and pharmaceutical compositions containing them MERCK & CO. INC. (US) 1981-04-15 EP disclosed
US-4241214-A BACTERICIDE, FUNGICIDE AND ALGAECIDE ROHM AND HAAS COMPANY (US) 1980-12-23 US disclosed
US-4195023-A ELASTASE INHIBITORS, TREATMENT OF EMPHYSEMA MERCK & CO., INC. (US) 1980-03-25 US disclosed
US-4195023-A ELASTASE INHIBITORS, TREATMENT OF EMPHYSEMA MERCK & CO., INC. (US) 1980-03-25 US disclosed
US-4150026-A BACTERICIDES, FUNGICIDES, ALGICIDES ROHM AND HAAS COMPANY (US) 1979-04-17 US disclosed
US-4062946-A 3-ISOTHIAZOLONES ROHM AND HAAS COMPANY (US) 1977-12-13 US disclosed