SCHEMBL8621525

SCHEMBL8621525

CCCCCCCCCCn1sc2ccccc2c1=O

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
FAAH O00519 1/20 1.00
MGLL Q99685 1/20 1.00
CASP3 P42574 5/20 0.66
KAT2A Q92830 1/20 0.62
KAT2B Q92831 1/20 0.62
G6PD P11413 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1538479 1.00 FAAH (1.00) FAAHMGLLCASP3KAT2AKAT2B
SCHEMBL8621594 1.00 FAAH (1.00) FAAHMGLLCASP3KAT2AKAT2B
SCHEMBL1538488 1.00 FAAH (1.00) FAAHMGLLCASP3KAT2AKAT2B
SCHEMBL11185114 1.00 FAAH (1.00) FAAHMGLLCASP3KAT2AKAT2B
SCHEMBL27971645 1.00 FAAH (1.00) FAAHMGLLCASP3KAT2AKAT2B
SCHEMBL24327898 1.00 FAAH (1.00) FAAHMGLLCASP3KAT2AKAT2B
SCHEMBL3147758 0.98 FAAH (0.97) FAAHMGLLCASP3KAT2AKAT2B
SCHEMBL16601156 0.94 FAAH (0.88) FAAHMGLLCASP3KAT2AKAT2B
SCHEMBL203818 0.94 FAAH (0.88) FAAHMGLLCASP3KAT2AKAT2B
SCHEMBL29370720 0.94 FAAH (0.88) FAAHMGLLCASP3KAT2AKAT2B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5744609-A REACTING AN ALKYLTHIOBENZAMIDE WITH A HALOGEN IN A HETEROGENOUS SOLVENT TO GIVE ALKYLSULFURYLBENZAMIDES INTERMEDIATES; USEFUL ANTIBACTERIAL AND ANTIFUNGAL AGENT SUMITOMO SEIKA CHEMICALS CO., LTD. (JP) 1998-04-28 US disclosed
US-5672751-A TREATMENT OF A HALOBENZAMIDE WITH AN ALKANETHIOL IN THE PRESENCE OF A PHASE TRANSFER CATALYST SUMITOMO SEIKA CHEMICALS CO., LTD. (JP) 1997-09-30 US disclosed
EP-0657438-B1 Method for producing 1,2-benzisothiazol-3-ones SUMITOMO SEIKA CHEMICALS (JP) 1997-07-30 EP disclosed
EP-0751123-A2 Method for producing alkylsulfinylbenzamides SUMITOMO SEIKA CHEMICALS CO., LTD. (JP) 1997-01-02 EP disclosed
US-5508416-A HALOGENATING A 2-(ALKYLTHIO)BENZAMIDE, CYCLIZATION TO HETERO RING AND N-S LINKAGE SUMITOMO SEIKA CHEMICALS CO., LTD. (JP) 1996-04-16 US disclosed
EP-0657438-A2 Method for producing alkylsulfinylbenzamides and 1,2-benzisothiazol-3-ones SUMITOMO SEIKA CHEMICALS CO., LTD. (JP) 1995-06-14 EP disclosed