Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 15/20 | 0.74 |
| ▸ | DRD2 | P14416 | 15/20 | 0.74 |
| ▸ | HTR2C | P28335 | 5/20 | 0.74 |
| ▸ | ADRA1A | P35348 | 5/20 | 0.74 |
| ▸ | HRH1 | P35367 | 5/20 | 0.74 |
| ▸ | KCNH2 | Q12809 | 5/20 | 0.74 |
| ▸ | ADRA2A | P08913 | 4/20 | 0.74 |
| ▸ | DRD3 | P35462 | 4/20 | 0.74 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.74 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.74 |
| ▸ | DRD1 | P21728 | 2/20 | 0.74 |
| ▸ | DRD4 | P21917 | 2/20 | 0.74 |
| ▸ | DRD5 | P21918 | 2/20 | 0.74 |
| ▸ | HTR1D | P28221 | 2/20 | 0.74 |
| ▸ | HTR1B | P28222 | 2/20 | 0.74 |
| ▸ | HTR7 | P34969 | 2/20 | 0.74 |
| ▸ | SCN5A | Q14524 | 2/20 | 0.74 |
| ▸ | KCND3 | Q9UK17 | 1/20 | 0.74 |
| ▸ | HTR1A | P08908 | 6/20 | 0.65 |
| ▸ | HTR6 | P50406 | 4/20 | 0.65 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6883333 | 0.92 | HTR2A (0.75) | HTR2ADRD2HTR2CADRA1AHRH1 | |
| Hydrochloric Acid SCHEMBL3147935 | 0.92 | HTR2A (0.74) | HTR2ADRD2HTR2CADRA1AHRH1 | |
| SCHEMBL12428786 | 0.92 | DRD2 (0.78) | HTR2ADRD2HTR2CADRA1AHRH1 | |
| SCHEMBL15489518 | 0.90 | DRD2 (0.74) | HTR2ADRD2HTR2CADRA1AHRH1 | |
| SCHEMBL19484373 | 0.90 | HTR2A (0.76) | HTR2ADRD2HTR2CADRA1AHRH1 | |
| SCHEMBL18849833 | 0.90 | HTR2A (0.75) | HTR2ADRD2HTR2CADRA1AHRH1 | |
| SCHEMBL3152563 | 0.90 | DRD2 (0.75) | HTR2ADRD2HTR2CADRA1AHRH1 | |
| Hydrochloric Acid SCHEMBL3151890 | 0.89 | HTR2A (0.71) | HTR2ADRD2HTR2CADRA1AHRH1 | |
| Hydrochloric Acid SCHEMBL3139414 | 0.89 | DRD2 (0.71) | HTR2ADRD2HTR2CADRA1AHRH1 | |
| SCHEMBL7979151 | 0.89 | DRD2 (0.81) | HTR2ADRD2HTR2CADRA1AHRH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2154138-B1 | NOVEL COMPOUNDS FOR TREATMENT OF PSYCHOTIC DISORDERS, PREPARATION METHODS AND USES THEREOF | LI YOUXIN (CN) | 2015-08-19 | — | — | EP | disclosed |
| EP-2154138-A1 | NOVEL COMPOUNDS FOR TREATMENT OF PSYCHOTIC DISORDERS, PREPARATION METHODS AND USES THEREOF | Li, Youxin (CN) | 2010-02-17 | — | — | EP | disclosed |