Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.57 |
| ▸ | HPGD | P15428 | 2/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.57 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.57 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.57 |
| ▸ | TSHR | P16473 | 1/20 | 0.57 |
| ▸ | LMNA | P02545 | 1/20 | 0.55 |
| ▸ | HRH1 | P35367 | 1/20 | 0.55 |
| ▸ | POLB | P06746 | 1/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.52 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.52 |
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15480448 | 0.82 | ALDH1A1 (0.67) | ALDH1A1HPGDSMN1; SMN2NPSR1HSD17B10 | |
| SCHEMBL15480450 | 0.82 | ALDH1A1 (0.67) | ALDH1A1HPGDSMN1; SMN2NPSR1HSD17B10 | |
| SCHEMBL15480447 | 0.82 | ALDH1A1 (0.67) | ALDH1A1HPGDSMN1; SMN2NPSR1HSD17B10 | |
| SCHEMBL15480445 | 0.82 | ALDH1A1 (0.67) | ALDH1A1HPGDSMN1; SMN2NPSR1HSD17B10 | |
| SCHEMBL15480444 | 0.80 | ALDH1A1 (0.68) | ALDH1A1HPGDSMN1; SMN2NPSR1HSD17B10 | |
| SCHEMBL31478767 | 0.78 | CA1 (0.47) | SMN1; SMN2LMNAKMT2AGAA | |
| SCHEMBL11224576 | 0.78 | CASR (0.55) | MAPTALDH1A1SMN1; SMN2NPSR1TSHR | |
| SCHEMBL18956497 | 0.77 | HPGD (0.50) | MAPTALDH1A1HPGDSMN1; SMN2NPSR1 | |
| SCHEMBL7934381 | 0.76 | ALDH1A1 (0.64) | ALDH1A1HPGDSMN1; SMN2NPSR1HSD17B10 | |
| SCHEMBL8232990 | 0.76 | ALDH1A1 (0.60) | ALDH1A1HPGDSMN1; SMN2NPSR1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250084074-A1 | SUBSTITUTED HETEROCYCLES AS HSET INHIBITORS | MERCK PATENT GMBH (DE) | 2025-03-13 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250084074-A1 | SUBSTITUTED HETEROCYCLES AS HSET INHIBITORS | VHL, CDKN1A, CCNI | MAPT 3266/4885ALDH1A1 1680/4885HPGD 204/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.