Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.42 |
| ▸ | HTR2A | P28223 | 3/20 | 0.36 |
| ▸ | DRD3 | P35462 | 3/20 | 0.36 |
| ▸ | DRD2 | P14416 | 2/20 | 0.36 |
| ▸ | PIK3CD | O00329 | 3/20 | 0.33 |
| ▸ | PIK3R1 | P27986 | 3/20 | 0.33 |
| ▸ | MELK | Q14680 | 4/20 | 0.31 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.30 |
| ▸ | F10 | P00742 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31478977 | 0.91 | KCNH2 (0.49) | MEN1KMT2AKCNH2HTR2ADRD3 | |
| SCHEMBL31479210 | 0.91 | KCNH2 (0.49) | MEN1KMT2AKCNH2HTR2ADRD3 | |
| SCHEMBL31479313 | 0.91 | KCNH2 (0.49) | MEN1KMT2AKCNH2HTR2ADRD3 | |
| SCHEMBL31479231 | 0.81 | MEN1 (0.49) | MEN1KMT2AKCNH2HTR2ADRD3 | |
| SCHEMBL31479357 | 0.79 | KDM4E (0.38) | KMT2A | |
| SCHEMBL31479895 | 0.79 | KCNH2 (0.49) | MEN1KMT2AKCNH2HTR2ADRD3 | |
| SCHEMBL31479419 | 0.79 | MEN1 (0.49) | MEN1KMT2AKCNH2HTR2ADRD3 | |
| SCHEMBL31479874 | 0.78 | TRPV3 (0.40) | PIK3CD | |
| SCHEMBL31478961 | 0.77 | CKS1B (0.36) | DRD2LIPG | |
| SCHEMBL31479856 | 0.73 | CHEK1 (0.34) | KMT2AKCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025067111-A1 | MENIN-MLL INTERACTION INHIBITOR AND PREPARATION METHOD THEREFOR, AND APPLICATION | 苏州必扬医药科技有限公司 | 2025-04-03 | — | — | WO | disclosed |