SCHEMBL31478992

SCHEMBL31478992

CC(C)N(CC(F)F)C(=O)c1cc(F)ccc1-c1cc(CC2CNC2)cc2c1cnn2C

nearest known ligand 0.34

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
SSTR4 P31391 2/20 0.34
GRIN2B Q13224 1/20 0.33
MAPK14 Q16539 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31479846 0.94 SLC6A2 (0.34) SSTR4GRIN2BMAPK14
SCHEMBL31479604 0.94 SLC6A2 (0.34) SSTR4GRIN2BMAPK14
SCHEMBL31479685 0.94 SLC6A2 (0.34) SSTR4GRIN2BMAPK14
SCHEMBL31478972 0.87 SSTR4 (0.33) SSTR4MAPK14
SCHEMBL31479195 0.86 PLK1 (0.36)
SCHEMBL31479142 0.83 GPR119 (0.38)
SCHEMBL31479742 0.83 GPR119 (0.38)
SCHEMBL31479005 0.83 GPR119 (0.38)
SCHEMBL31479424 0.83 SLC6A2 (0.35) SSTR4MAPK14
SCHEMBL31479663 0.82 SLC6A2 (0.33) SSTR4MAPK14

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025067111-A1 MENIN-MLL INTERACTION INHIBITOR AND PREPARATION METHOD THEREFOR, AND APPLICATION 苏州必扬医药科技有限公司 2025-04-03 WO disclosed