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Sugi Predict / Compounds / SCHEMBL31479142

SCHEMBL31479142

SCHEMBL31479142

CC(C)N(CC(F)F)C(=O)c1cc(F)ccc1-c1cc(CC2CCN(C(=O)OC(C)(C)C)C2)cc2c1cnn2C

nearest known ligand 0.39

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
▸ GPR119 Q8TDV5 3/20 0.38
▸ ALOX5AP P20292 3/20 0.37
▸ FEN1 P39748 3/20 0.37
▸ TP53 P04637 2/20 0.36
▸ LMNA P02545 1/20 0.36
▸ BRD3 Q15059 1/20 0.36
▸ SMN1; SMN2 Q16637 1/20 0.35
▸ PIK3CD O00329 1/20 0.35
▸ IDO1 P14902 1/20 0.34
▸ TDO2 P48775 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31479005 1.00 GPR119 (0.38) GPR119ALOX5APFEN1TP53LMNA
SCHEMBL31479742 1.00 GPR119 (0.38) GPR119ALOX5APFEN1TP53LMNA
SCHEMBL31479195 0.94 PLK1 (0.36) GPR119ALOX5APFEN1TP53LMNA
SCHEMBL31479136 0.88 GPR119 (0.39) GPR119ALOX5APFEN1TP53SMN1; SMN2
SCHEMBL31479066 0.88 GPR119 (0.39) GPR119ALOX5APFEN1TP53SMN1; SMN2
SCHEMBL31479646 0.88 GPR119 (0.39) GPR119ALOX5APFEN1TP53SMN1; SMN2
SCHEMBL31479791 0.86 ALOX5AP (0.39) GPR119ALOX5APFEN1SMN1; SMN2
SCHEMBL31479405 0.85 GPBAR1 (0.41) GPR119ALOX5APFEN1TP53SMN1; SMN2
SCHEMBL31478992 0.83 SSTR4 (0.34) —
SCHEMBL31479685 0.82 SLC6A2 (0.34) —

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025067111-A1 MENIN-MLL INTERACTION INHIBITOR AND PREPARATION METHOD THEREFOR, AND APPLICATION 苏州必扬医药科技有限公司 2025-04-03 — — WO disclosed